Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation

In recent years, small pancreatic neuroendocrine tumors (pNETs) have shown a dramatic increase in terms of incidence and prevalence, and endoscopic ultrasound (EUS) radiofrequency ablation (RFA) is one potential method to treat the disease in selected patients. As well as the heterogeneity of pNET h...

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Main Authors: Gemma Rossi, Maria Chiara Petrone, Andrew J. Healey, Paolo Giorgio Arcidiacono
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/9/1561
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author Gemma Rossi
Maria Chiara Petrone
Andrew J. Healey
Paolo Giorgio Arcidiacono
author_facet Gemma Rossi
Maria Chiara Petrone
Andrew J. Healey
Paolo Giorgio Arcidiacono
author_sort Gemma Rossi
collection DOAJ
description In recent years, small pancreatic neuroendocrine tumors (pNETs) have shown a dramatic increase in terms of incidence and prevalence, and endoscopic ultrasound (EUS) radiofrequency ablation (RFA) is one potential method to treat the disease in selected patients. As well as the heterogeneity of pNET histology, the studies reported in the literature on EUS-RFA procedures for pNETs are heterogeneous in terms of ablation settings (particularly ablation powers), radiological controls, and radiological indications. The aim of this review is to report the current reported experience in EUS-RFA of small pNETs to help formulate the procedure indications and ablation settings. Another aim is to evaluate the timing and the modality of the radiological surveillance after the ablation. Moreover, new studies on large-scale series are needed in terms of the safety and long-term oncological efficacy of RFA on these small lesions.
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spelling doaj.art-9bafa4fcac0440b28788a9de2391c1462023-11-17T22:45:22ZengMDPI AGDiagnostics2075-44182023-04-01139156110.3390/diagnostics13091561Approaching Small Neuroendocrine Tumors with Radiofrequency AblationGemma Rossi0Maria Chiara Petrone1Andrew J. Healey2Paolo Giorgio Arcidiacono3Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita Salute San Raffaele University, 20132 Milan, ItalyPancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita Salute San Raffaele University, 20132 Milan, ItalyDepartment of Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UKPancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita Salute San Raffaele University, 20132 Milan, ItalyIn recent years, small pancreatic neuroendocrine tumors (pNETs) have shown a dramatic increase in terms of incidence and prevalence, and endoscopic ultrasound (EUS) radiofrequency ablation (RFA) is one potential method to treat the disease in selected patients. As well as the heterogeneity of pNET histology, the studies reported in the literature on EUS-RFA procedures for pNETs are heterogeneous in terms of ablation settings (particularly ablation powers), radiological controls, and radiological indications. The aim of this review is to report the current reported experience in EUS-RFA of small pNETs to help formulate the procedure indications and ablation settings. Another aim is to evaluate the timing and the modality of the radiological surveillance after the ablation. Moreover, new studies on large-scale series are needed in terms of the safety and long-term oncological efficacy of RFA on these small lesions.https://www.mdpi.com/2075-4418/13/9/1561endoscopic ultrasoundradiofrequency ablationneuroendocrine tumors
spellingShingle Gemma Rossi
Maria Chiara Petrone
Andrew J. Healey
Paolo Giorgio Arcidiacono
Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
Diagnostics
endoscopic ultrasound
radiofrequency ablation
neuroendocrine tumors
title Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
title_full Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
title_fullStr Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
title_full_unstemmed Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
title_short Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
title_sort approaching small neuroendocrine tumors with radiofrequency ablation
topic endoscopic ultrasound
radiofrequency ablation
neuroendocrine tumors
url https://www.mdpi.com/2075-4418/13/9/1561
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AT paologiorgioarcidiacono approachingsmallneuroendocrinetumorswithradiofrequencyablation