Driving forces in the origins of life
What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a ‘proteins...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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The Royal Society
2021-02-01
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| Series: | Open Biology |
| Subjects: | |
| Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200324 |
| _version_ | 1830131822056439808 |
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| author | K. A. Dill L. Agozzino |
| author_facet | K. A. Dill L. Agozzino |
| author_sort | K. A. Dill |
| collection | DOAJ |
| description | What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a ‘proteins-first’ world gives plausible mechanisms. We note the importance of hydrophobic and polar compositions of matter in these advances. |
| first_indexed | 2024-12-17T06:23:09Z |
| format | Article |
| id | doaj.art-9bb3f233a2ea440b9bb66a44922bf7ad |
| institution | Directory Open Access Journal |
| issn | 2046-2441 |
| language | English |
| last_indexed | 2024-12-17T06:23:09Z |
| publishDate | 2021-02-01 |
| publisher | The Royal Society |
| record_format | Article |
| series | Open Biology |
| spelling | doaj.art-9bb3f233a2ea440b9bb66a44922bf7ad2022-12-21T22:00:21ZengThe Royal SocietyOpen Biology2046-24412021-02-0111210.1098/rsob.200324200324Driving forces in the origins of lifeK. A. DillL. AgozzinoWhat were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We describe how a ‘proteins-first’ world gives plausible mechanisms. We note the importance of hydrophobic and polar compositions of matter in these advances.https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200324origin of lifesurvival of the fittestautocatalysisfitness |
| spellingShingle | K. A. Dill L. Agozzino Driving forces in the origins of life Open Biology origin of life survival of the fittest autocatalysis fitness |
| title | Driving forces in the origins of life |
| title_full | Driving forces in the origins of life |
| title_fullStr | Driving forces in the origins of life |
| title_full_unstemmed | Driving forces in the origins of life |
| title_short | Driving forces in the origins of life |
| title_sort | driving forces in the origins of life |
| topic | origin of life survival of the fittest autocatalysis fitness |
| url | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200324 |
| work_keys_str_mv | AT kadill drivingforcesintheoriginsoflife AT lagozzino drivingforcesintheoriginsoflife |