Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma

Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma

More than 35% of lung adenocarcinoma patients have bone metastases at diagnosis and have a poor survival. Periostin, a carboxylated matrix protein, mediates lung cancer cell dissemination by promoting epithelial-mesenchymal transition, and is involved in bone response to mechanical stress and bone f...

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Bibliographic Details
Main Authors: E Massy, JC. Rousseau, M. Gueye, E. Bonnelye, M. Brevet, L. Chambard, M. Duruisseaux, O. Borel, C. Roger, R. Guelminger, J.B. Pialat, E. Gineyts, L. Bouazza, M. Millet, JM. Maury, P. Clézardin, N. Girard, Cyrille B. Confavreux
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Bone Oncology
Subjects:
Bone metastasis
Periostin
Lung cancer
Serum biomarker
Survival
Online Access:http://www.sciencedirect.com/science/article/pii/S221213742100018X

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