Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state
To become infectious, HIV-1 particles undergo a maturation process involving the clustering of envelope glycoprotein Env. Here, Chojnacki et al. employ super-resolution STED-FCS microscopy to study dynamics of Env molecules on HIV-1 particles and show that Env undergoes a maturation-induced increase...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00515-6 |
| _version_ | 1818991142010617856 |
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| author | Jakub Chojnacki Dominic Waithe Pablo Carravilla Nerea Huarte Silvia Galiani Jörg Enderlein Christian Eggeling |
| author_facet | Jakub Chojnacki Dominic Waithe Pablo Carravilla Nerea Huarte Silvia Galiani Jörg Enderlein Christian Eggeling |
| author_sort | Jakub Chojnacki |
| collection | DOAJ |
| description | To become infectious, HIV-1 particles undergo a maturation process involving the clustering of envelope glycoprotein Env. Here, Chojnacki et al. employ super-resolution STED-FCS microscopy to study dynamics of Env molecules on HIV-1 particles and show that Env undergoes a maturation-induced increase in mobility. |
| first_indexed | 2024-12-20T20:05:33Z |
| format | Article |
| id | doaj.art-9bb82829df914397bfa31c4a7f2034a3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T20:05:33Z |
| publishDate | 2017-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9bb82829df914397bfa31c4a7f2034a32022-12-21T19:27:57ZengNature PortfolioNature Communications2041-17232017-09-018111010.1038/s41467-017-00515-6Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation stateJakub Chojnacki0Dominic Waithe1Pablo Carravilla2Nerea Huarte3Silvia Galiani4Jörg Enderlein5Christian Eggeling6MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of OxfordWolfson Imaging Centre, Weatherall Institute of Molecular Medicine, University of OxfordBiofisika Institute (UPV/EHU, CSIC) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU)Biofisika Institute (UPV/EHU, CSIC) and Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU)MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of OxfordThird Institute of Physics, Georg August UniversityMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of OxfordTo become infectious, HIV-1 particles undergo a maturation process involving the clustering of envelope glycoprotein Env. Here, Chojnacki et al. employ super-resolution STED-FCS microscopy to study dynamics of Env molecules on HIV-1 particles and show that Env undergoes a maturation-induced increase in mobility.https://doi.org/10.1038/s41467-017-00515-6 |
| spellingShingle | Jakub Chojnacki Dominic Waithe Pablo Carravilla Nerea Huarte Silvia Galiani Jörg Enderlein Christian Eggeling Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state Nature Communications |
| title | Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state |
| title_full | Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state |
| title_fullStr | Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state |
| title_full_unstemmed | Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state |
| title_short | Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state |
| title_sort | envelope glycoprotein mobility on hiv 1 particles depends on the virus maturation state |
| url | https://doi.org/10.1038/s41467-017-00515-6 |
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