UHPLC-MS/MS profiling of histidine and bile acid metabolism in human gastric fluid for diagnosis of gastric diseases

UHPLC-MS/MS profiling of histidine and bile acid metabolism in human gastric fluid for diagnosis of gastric diseases

Abstract Bile acids (BAs) are synthesized in the liver and can mediate homeostasis and various metabolism processes in the human body. Their levels in the gastrointestinal tract are closely related to various gastrointestinal diseases. In particular, farnesoid X receptor activated by free BAs is ass...

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Bibliographic Details
Main Authors:	Wonwoong Lee, Jinhee Um, Keon-hee Ko, Yong Chan Lee, Bong Chul Chung, Jongki Hong
Format:	Article
Language:	English
Published:	SpringerOpen 2020-06-01
Series:	Journal of Analytical Science and Technology
Subjects:	Bile acids Histidine Histamine UHPLC-MS/MS-MRM Profiling analysis Serial derivatization
Online Access:	http://link.springer.com/article/10.1186/s40543-020-00218-6

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