Impact of Variants in the <i>ATIC</i> and <i>ARID5B</i> Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia

Impact of Variants in the <i>ATIC</i> and <i>ARID5B</i> Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm derived from the balanced reciprocal translocation of chromosomes 9 and 22 t (9q34 and 22q11), which leads to the formation of the Philadelphia chromosome and fusion of the <i>BCR-ABL</i> genes. The first-line treatment for...

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Bibliographic Details
Main Authors:	Karla Beatriz Cardias Cereja Pantoja, Tereza Cristina de Brito Azevedo, Darlen Cardoso de Carvalho, Natasha Monte, Amanda de Nazaré Cohen Paes, Maria Clara da Costa Barros, Lui Wallacy Morikawa Souza Vinagre, Ana Rosa Sales de Freitas, Rommel Mario Rodríguez Burbano, Paulo Pimentel de Assumpção, Sidney Emanuel Batista dos Santos, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Genes
Subjects:	chronic myeloid leukemia imatinib <i>ATIC</i> gene <i>ARIDB5</i> gene pharmacogenomics
Online Access:	https://www.mdpi.com/2073-4425/13/2/330

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