Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain
Improved understanding of psychological features associated with full mu agonist long-term opioid therapy (LTOT) cessation may offer advantages for clinicians. This preliminary study presents changes in psychological outcomes in patients with chronic, non-cancer pain (CNCP) after LTOT cessation via...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/4/1354 |
| _version_ | 1797620209039704064 |
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| author | Marcelina Jasmine Silva Zhanette Coffee Chong Ho Alex Yu Joshua Hu |
| author_facet | Marcelina Jasmine Silva Zhanette Coffee Chong Ho Alex Yu Joshua Hu |
| author_sort | Marcelina Jasmine Silva |
| collection | DOAJ |
| description | Improved understanding of psychological features associated with full mu agonist long-term opioid therapy (LTOT) cessation may offer advantages for clinicians. This preliminary study presents changes in psychological outcomes in patients with chronic, non-cancer pain (CNCP) after LTOT cessation via a 10-week multidisciplinary program which included treatment with buprenorphine. Paired <i>t</i>-tests pre- and post-LTOT cessation were compared in this retrospective cohort review of data from electronic medical records of 98 patients who successfully ceased LTOT between the dates of October 2017 to December 2019. Indicators of quality of life, depression, catastrophizing, and fear avoidance, as measured by the 36-Item Short Form Survey, the Patient Health Questionnaire-9-Item Scale, the Pain Catastrophizing Scale, and the Fear Avoidance Belief Questionnaires revealed significant improvement. Scores did not significantly improve for daytime sleepiness, generalized anxiety, and kinesiophobia, as measured by the Epworth Sleepiness Scale, the Generalized Anxiety Disorder 7-Item Scale, and the Tampa Scale of Kinesiophobia. The results suggest that successful LTOT cessation may be interconnected with improvements in specific psychological states. |
| first_indexed | 2024-03-11T08:38:53Z |
| format | Article |
| id | doaj.art-9bbf7ccde78541f0847543b93a173a08 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T08:38:53Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-9bbf7ccde78541f0847543b93a173a082023-11-16T21:18:22ZengMDPI AGJournal of Clinical Medicine2077-03832023-02-01124135410.3390/jcm12041354Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic PainMarcelina Jasmine Silva0Zhanette Coffee1Chong Ho Alex Yu2Joshua Hu3The Focus on Opioid Transitions (FOOT Steps) Program, IPM Medical Group, Walnut Creek, CA 94598, USACollege of Nursing, University of Arizona, Tucson, AZ 85721, USAOffice of Institutional Research, Azusa Pacific University, Azusa, CA 91702, USACollege of Osteopathic Medicine, Touro University, Vallejo, CA 94592, USAImproved understanding of psychological features associated with full mu agonist long-term opioid therapy (LTOT) cessation may offer advantages for clinicians. This preliminary study presents changes in psychological outcomes in patients with chronic, non-cancer pain (CNCP) after LTOT cessation via a 10-week multidisciplinary program which included treatment with buprenorphine. Paired <i>t</i>-tests pre- and post-LTOT cessation were compared in this retrospective cohort review of data from electronic medical records of 98 patients who successfully ceased LTOT between the dates of October 2017 to December 2019. Indicators of quality of life, depression, catastrophizing, and fear avoidance, as measured by the 36-Item Short Form Survey, the Patient Health Questionnaire-9-Item Scale, the Pain Catastrophizing Scale, and the Fear Avoidance Belief Questionnaires revealed significant improvement. Scores did not significantly improve for daytime sleepiness, generalized anxiety, and kinesiophobia, as measured by the Epworth Sleepiness Scale, the Generalized Anxiety Disorder 7-Item Scale, and the Tampa Scale of Kinesiophobia. The results suggest that successful LTOT cessation may be interconnected with improvements in specific psychological states.https://www.mdpi.com/2077-0383/12/4/1354chronic painopioidspatient experiencespsychological outcomesmanagementtreatment |
| spellingShingle | Marcelina Jasmine Silva Zhanette Coffee Chong Ho Alex Yu Joshua Hu Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain Journal of Clinical Medicine chronic pain opioids patient experiences psychological outcomes management treatment |
| title | Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain |
| title_full | Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain |
| title_fullStr | Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain |
| title_full_unstemmed | Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain |
| title_short | Changes in Psychological Outcomes after Cessation of Full Mu Agonist Long-Term Opioid Therapy for Chronic Pain |
| title_sort | changes in psychological outcomes after cessation of full mu agonist long term opioid therapy for chronic pain |
| topic | chronic pain opioids patient experiences psychological outcomes management treatment |
| url | https://www.mdpi.com/2077-0383/12/4/1354 |
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