Harnessing Lipid Polymer Hybrid Nanoparticles for Enhanced Oral Bioavailability of Thymoquinone: In Vitro and In Vivo Assessments
The clinical application of phytochemicals such as thymoquinone (THQ) is restricted due to their limited aqueous solubility and oral bioavailability. Developing mucoadhesive nanocarriers to deliver these natural compounds might provide new hope to enhance their oral bioavailability. Herein, this inv...
Main Authors: | Syed Sarim Imam, Sadaf Jamal Gilani, May Nasser Bin Jumah, Md. Rizwanullah, Ameeduzzafar Zafar, Mohammed Muqtader Ahmed, Sultan Alshehri |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-09-01
|
Series: | Polymers |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4360/14/18/3705 |
Similar Items
-
Recent Advancement in Chitosan-Based Nanoparticles for Improved Oral Bioavailability and Bioactivity of Phytochemicals: Challenges and Perspectives
by: Syed Sarim Imam, et al.
Published: (2021-11-01) -
Response of Skin-Derived and Metastatic Human Malignant Melanoma Cell Lines to Thymoquinone and Thymoquinone-Loaded Liposomes
by: Patrycja Kłos, et al.
Published: (2022-10-01) -
Development of Stable Liposomal Drug Delivery System of Thymoquinone and Its In Vitro Anticancer Studies Using Breast Cancer and Cervical Cancer Cell Lines
by: Mohammad Hossain Shariare, et al.
Published: (2022-10-01) -
Formulation of Miconazole-Loaded Chitosan–Carbopol Vesicular Gel: Optimization to In Vitro Characterization, Irritation, and Antifungal Assessment
by: Syed Sarim Imam, et al.
Published: (2023-02-01) -
Ameliorative Effect of Thymoquinone and Thymoquinone Nanoparticles against Diazinon-Induced Hepatic Injury in Rats: A Possible Protection Mechanism
by: Walaa M. Nassar, et al.
Published: (2023-09-01)