Penicillamine-induced virginal mammary hypertrophy
Virginal mammary hypertrophy (VMH), also known as juvenile mammary hypertrophy, is characterized by excessive enlargement of the breasts. Especially in adolescent patients, this condition can cause a negative body image to develop and result in significant psychological stress. Furthermore, social p...
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| Format: | Article |
| Language: | English |
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Korean Society for Aesthetic Plastic Surgery
2021-01-01
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| Series: | Archives of Aesthetic Plastic Surgery |
| Subjects: | |
| Online Access: | http://e-aaps.org/upload/pdf/aaps-2020-02376.pdf |
| _version_ | 1831674108203499520 |
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| author | Daiwon Jun Na Rim Kim Young Chul Suh Young Jin Kim Kyoung Soon Cho Jung Ho Lee |
| author_facet | Daiwon Jun Na Rim Kim Young Chul Suh Young Jin Kim Kyoung Soon Cho Jung Ho Lee |
| author_sort | Daiwon Jun |
| collection | DOAJ |
| description | Virginal mammary hypertrophy (VMH), also known as juvenile mammary hypertrophy, is characterized by excessive enlargement of the breasts. Especially in adolescent patients, this condition can cause a negative body image to develop and result in significant psychological stress. Furthermore, social problems can arise from difficulties in finding appropriately-fitting attire and having trouble exercising. Although the mechanism of VMH has not been fully elucidated, several associated drugs have been identified. In this report, we present a 15-year-old female patient with Wilson disease who developed macromastia after administration of penicillamine for 8 months. Despite cessation of penicillamine for 3 months, the condition remained stable; thus, reduction mammoplasty was performed. After surgery, the patient was able to return to activities of daily living. Although rare, physicians should be aware of the fact that penicillamine can cause VHM. Therefore, patients with Wilson disease should be checked regularly for changes in breast volume in order to minimize possible complications. |
| first_indexed | 2024-12-20T03:38:14Z |
| format | Article |
| id | doaj.art-9bc36199f641452faf75acd26a64e44b |
| institution | Directory Open Access Journal |
| issn | 2234-0831 2288-9337 |
| language | English |
| last_indexed | 2024-12-20T03:38:14Z |
| publishDate | 2021-01-01 |
| publisher | Korean Society for Aesthetic Plastic Surgery |
| record_format | Article |
| series | Archives of Aesthetic Plastic Surgery |
| spelling | doaj.art-9bc36199f641452faf75acd26a64e44b2022-12-21T19:54:48ZengKorean Society for Aesthetic Plastic SurgeryArchives of Aesthetic Plastic Surgery2234-08312288-93372021-01-01271353810.14730/aaps.2020.02376728Penicillamine-induced virginal mammary hypertrophyDaiwon Jun0Na Rim Kim1Young Chul Suh2Young Jin Kim3Kyoung Soon Cho4Jung Ho Lee5 Department of Plastic and Reconstructive Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Plastic and Reconstructive Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Plastic and Reconstructive Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Plastic and Reconstructive Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Pediatrics, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea Department of Plastic and Reconstructive Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, KoreaVirginal mammary hypertrophy (VMH), also known as juvenile mammary hypertrophy, is characterized by excessive enlargement of the breasts. Especially in adolescent patients, this condition can cause a negative body image to develop and result in significant psychological stress. Furthermore, social problems can arise from difficulties in finding appropriately-fitting attire and having trouble exercising. Although the mechanism of VMH has not been fully elucidated, several associated drugs have been identified. In this report, we present a 15-year-old female patient with Wilson disease who developed macromastia after administration of penicillamine for 8 months. Despite cessation of penicillamine for 3 months, the condition remained stable; thus, reduction mammoplasty was performed. After surgery, the patient was able to return to activities of daily living. Although rare, physicians should be aware of the fact that penicillamine can cause VHM. Therefore, patients with Wilson disease should be checked regularly for changes in breast volume in order to minimize possible complications.http://e-aaps.org/upload/pdf/aaps-2020-02376.pdfwilson diseasepenicillaminebreast disease |
| spellingShingle | Daiwon Jun Na Rim Kim Young Chul Suh Young Jin Kim Kyoung Soon Cho Jung Ho Lee Penicillamine-induced virginal mammary hypertrophy Archives of Aesthetic Plastic Surgery wilson disease penicillamine breast disease |
| title | Penicillamine-induced virginal mammary hypertrophy |
| title_full | Penicillamine-induced virginal mammary hypertrophy |
| title_fullStr | Penicillamine-induced virginal mammary hypertrophy |
| title_full_unstemmed | Penicillamine-induced virginal mammary hypertrophy |
| title_short | Penicillamine-induced virginal mammary hypertrophy |
| title_sort | penicillamine induced virginal mammary hypertrophy |
| topic | wilson disease penicillamine breast disease |
| url | http://e-aaps.org/upload/pdf/aaps-2020-02376.pdf |
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