Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation
The purpose of this study was to investigate the effects of different dietary fiber compounds (DFCs) on characteristic human flora and their metabolites mediated by the longevity dietary pattern analyzed by in vitro fermentation. The results show that DFC1 (cereal fiber) increased the level of <i...
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MDPI AG
2022-11-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/23/5037 |
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| author | Fengcui Shi Fan Zhou Xiaohua Zheng Jingwen Lv Xiaohan Yu Yang Zhou Quanyang Li |
| author_facet | Fengcui Shi Fan Zhou Xiaohua Zheng Jingwen Lv Xiaohan Yu Yang Zhou Quanyang Li |
| author_sort | Fengcui Shi |
| collection | DOAJ |
| description | The purpose of this study was to investigate the effects of different dietary fiber compounds (DFCs) on characteristic human flora and their metabolites mediated by the longevity dietary pattern analyzed by in vitro fermentation. The results show that DFC1 (cereal fiber) increased the level of <i>Lactobacillus</i> (<i>p</i> < 0.05), DFC2 (fruit and vegetable and cereal fiber) promoted the growth of <i>Lactobacillus</i> and <i>Bifidobacterium</i> more significantly than DFC3 (fruit and vegetable fiber) (<i>p</i> < 0.01), and all three DFCs decreased the level of <i>Escherichia coli</i> (<i>p</i> < 0.05). The metabolomic analysis showed that there was variability in the metabolites and the metabolic pathways of different DFCs. The redundancy analysis revealed that the fiber content was positively correlated with <i>Lactobacillus</i>, <i>Bifidobacterium</i>, <i>Bacteroides</i>, acetic acid, butyric acid, propionic acid, lactic acid, and betaine, and negatively correlated with <i>Escherichia coli</i>, succinic acid, alanine, choline, aspartic acid, and α-glucose. Overall, this study found that different DFCs have different positive correlations on characteristic human flora and metabolites, and DFC2 is more favorable to the proliferation of the intestinal beneficial genera <i>Lactobacillus</i> and <i>Bifidobacterium</i> after in vitro fermentation, having a probiotic role in glucose, amino acid, and lipid metabolisms. This study may provide a theoretical reference for the search of optimal dietary fiber combination strategies mediated by longevity dietary pattern. |
| first_indexed | 2024-03-09T17:37:53Z |
| format | Article |
| id | doaj.art-9bc5ca8aa0354c838affa459e2886174 |
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| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T17:37:53Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-9bc5ca8aa0354c838affa459e28861742023-11-24T11:51:07ZengMDPI AGNutrients2072-66432022-11-011423503710.3390/nu14235037Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro FermentationFengcui Shi0Fan Zhou1Xiaohua Zheng2Jingwen Lv3Xiaohan Yu4Yang Zhou5Quanyang Li6College of Light Industry and Food Engineering, Guangxi University, Nanning 530004, ChinaCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, ChinaCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, ChinaCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, ChinaCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, ChinaWangdingdi Hospital, Tianjin Nankai District, Tianjin 300191, ChinaCollege of Light Industry and Food Engineering, Guangxi University, Nanning 530004, ChinaThe purpose of this study was to investigate the effects of different dietary fiber compounds (DFCs) on characteristic human flora and their metabolites mediated by the longevity dietary pattern analyzed by in vitro fermentation. The results show that DFC1 (cereal fiber) increased the level of <i>Lactobacillus</i> (<i>p</i> < 0.05), DFC2 (fruit and vegetable and cereal fiber) promoted the growth of <i>Lactobacillus</i> and <i>Bifidobacterium</i> more significantly than DFC3 (fruit and vegetable fiber) (<i>p</i> < 0.01), and all three DFCs decreased the level of <i>Escherichia coli</i> (<i>p</i> < 0.05). The metabolomic analysis showed that there was variability in the metabolites and the metabolic pathways of different DFCs. The redundancy analysis revealed that the fiber content was positively correlated with <i>Lactobacillus</i>, <i>Bifidobacterium</i>, <i>Bacteroides</i>, acetic acid, butyric acid, propionic acid, lactic acid, and betaine, and negatively correlated with <i>Escherichia coli</i>, succinic acid, alanine, choline, aspartic acid, and α-glucose. Overall, this study found that different DFCs have different positive correlations on characteristic human flora and metabolites, and DFC2 is more favorable to the proliferation of the intestinal beneficial genera <i>Lactobacillus</i> and <i>Bifidobacterium</i> after in vitro fermentation, having a probiotic role in glucose, amino acid, and lipid metabolisms. This study may provide a theoretical reference for the search of optimal dietary fiber combination strategies mediated by longevity dietary pattern.https://www.mdpi.com/2072-6643/14/23/5037longevity dietary patterndietary fiber compoundin vitro fermentationcharacteristic human florametabolites |
| spellingShingle | Fengcui Shi Fan Zhou Xiaohua Zheng Jingwen Lv Xiaohan Yu Yang Zhou Quanyang Li Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation Nutrients longevity dietary pattern dietary fiber compound in vitro fermentation characteristic human flora metabolites |
| title | Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation |
| title_full | Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation |
| title_fullStr | Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation |
| title_full_unstemmed | Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation |
| title_short | Effects of Dietary Fiber Compounds on Characteristic Human Flora and Metabolites Mediated by the Longevity Dietary Pattern Analyzed by In Vitro Fermentation |
| title_sort | effects of dietary fiber compounds on characteristic human flora and metabolites mediated by the longevity dietary pattern analyzed by in vitro fermentation |
| topic | longevity dietary pattern dietary fiber compound in vitro fermentation characteristic human flora metabolites |
| url | https://www.mdpi.com/2072-6643/14/23/5037 |
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