Epigenetic signatures in antidepressant treatment response: a methylome-wide association study in the EMC trial

Abstract Although the currently available antidepressants are well established in the treatment of the major depressive disorder (MDD), there is strong variability in the response of individual patients. Reliable predictors to guide treatment decisions before or in an early stage of treatment are ne...

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Bibliographic Details
Main Authors: J. Engelmann, L. Zillich, J. Frank, S. Wagner, M. Cetin, D. P. Herzog, M. B. Müller, A. Tadic, J. C. Foo, L. Sirignano, D. F. Braus, N. Dahmen, S. Sordon, M. Riemenschneider, C. Spaniol, G. Gasparoni, M. Rietschel, S. H. Witt, K. Lieb, F. Streit
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02032-7