Bostrychines A–F, Six Novel Mycosporine-Like Amino-Acids and a Novel Betaine from the Red Alga <i>Bostrychia scorpioides</i>

Various red algae have repeatedly been reported to produce a variety of UV-absorbing mycosporine-like amino acids (MAAs), compounds that are well-known as natural sun-screens, as well as a plethora of betaines, metabolites which contribute to the osmotic balance under salt stress. Among other Rhodop...

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Bibliographic Details
Main Authors: Maria Orfanoudaki, Anja Hartmann, Helena Miladinovic, Hieu Nguyen Ngoc, Ulf Karsten, Markus Ganzera
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/17/6/356
Description
Summary:Various red algae have repeatedly been reported to produce a variety of UV-absorbing mycosporine-like amino acids (MAAs), compounds that are well-known as natural sun-screens, as well as a plethora of betaines, metabolites which contribute to the osmotic balance under salt stress. Among other Rhodophyta, <i>Bostrychia scorpioides</i>, which is thriving as epiphyte on salt marsh plants in Europe and hence experiences extreme environmental conditions such as desiccation, UV-stress and osmotic stress, has barely been investigated for its secondary metabolites. In the present study, seven mycosporine like-amino acids and two betaines were isolated from <i>Bostrychia scorpioides</i> using various chromatographic techniques. Their structures were confirmed by Nuclear Magnetic Resonance (NMR) spectroscopy and High Resolution Mass Spectrometry (HRMS). Six MAAs and one betaine were chemically characterized as new natural products.
ISSN:1660-3397