Expanded Substrate Specificity in D-Amino Acid Transaminases: A Case Study of Transaminase from <i>Blastococcus saxobsidens</i>
Enzymes with expanded substrate specificity are good starting points for the design of biocatalysts for target reactions. However, the structural basis of the expanded substrate specificity is still elusive, especially in the superfamily of pyridoxal-5′-phosphate-dependent transaminases, which are c...
Main Authors: | Sofia A. Shilova, Ilya O. Matyuta, Elizaveta S. Petrova, Alena Y. Nikolaeva, Tatiana V. Rakitina, Mikhail E. Minyaev, Konstantin M. Boyko, Vladimir O. Popov, Ekaterina Yu. Bezsudnova |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/22/16194 |
Similar Items
-
Asymmetric Synthesis of Enantiomerically Pure Aliphatic and Aromatic D-Amino Acids Catalyzed by Transaminase from <i>Haliscomenobacter hydrossis</i>
by: Alina K. Bakunova, et al.
Published: (2022-12-01) -
To the Understanding of Catalysis by D-Amino Acid Transaminases: A Case Study of the Enzyme from <i>Aminobacterium colombiense</i>
by: Sofia A. Shilova, et al.
Published: (2023-02-01) -
A Puzzling Protein from <i>Variovorax paradoxus</i> Has a PLP Fold Type IV Transaminase Structure and Binds PLP without Catalytic Lysine
by: Konstantin M. Boyko, et al.
Published: (2022-04-01) -
Computer Modeling Explains the Structural Reasons for the Difference in Reactivity of Amine Transaminases Regarding Prochiral Methylketones
by: Iris S. Teixeira, et al.
Published: (2022-01-01) -
ω-Transaminase-Mediated Asymmetric Synthesis of (<i>S</i>)-1-(4-Trifluoromethylphenyl)Ethylamine
by: Carlos J. C. Rodrigues, et al.
Published: (2021-02-01)