Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance
Abstract Objectives To provide clinical validation of a recent 2D SENSE-based accelerated cardiovascular magnetic resonance (CMR) sequence (accelerated k-t SENSE), investigating whether this technique accurately quantifies left ventricle (LV) volumes, function, and mass as compared to 2D cine steady...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-06-01
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| Series: | Insights into Imaging |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13244-019-0750-6 |
| _version_ | 1811212007738703872 |
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| author | Antonildes Nascimento Assuncao-Jr Roberto Nery Dantas-Jr Renata Margarida do Val Priscilla Gianotto Angela dos Santos Marin Mark Golden Marco Antonio Gutierrez Jose Rodrigues Parga Cesar Higa Nomura |
| author_facet | Antonildes Nascimento Assuncao-Jr Roberto Nery Dantas-Jr Renata Margarida do Val Priscilla Gianotto Angela dos Santos Marin Mark Golden Marco Antonio Gutierrez Jose Rodrigues Parga Cesar Higa Nomura |
| author_sort | Antonildes Nascimento Assuncao-Jr |
| collection | DOAJ |
| description | Abstract Objectives To provide clinical validation of a recent 2D SENSE-based accelerated cardiovascular magnetic resonance (CMR) sequence (accelerated k-t SENSE), investigating whether this technique accurately quantifies left ventricle (LV) volumes, function, and mass as compared to 2D cine steady-state free precession (2D-SSFP). Methods Healthy volunteers (n = 16) and consecutive heart failure patients (n = 26) were scanned using a 1.5 T MRI system. Two LV short axis (SA) stacks were acquired: (1) accelerated k-t SENSE (5–6 breath-holds; temporal/spatial resolution: 37 ms/1.82 × 1.87 mm; acceleration factor = 4) and (2) standard 2D-SSFP (10–12 breath-holds; temporal/spatial resolution: 49 ms/1.67 × 1.87 mm, parallel imaging). Ascending aorta phase-contrast was performed on all volunteers as a reference to compare LV stroke volumes (LVSV) and validate the sequences. An image quality score for SA images was used, with lower scores indicating better quality (from 0 to 18). Results There was a high agreement between accelerated k-t SENSE and 2D-SSFP for LV measurements: bias (limits of agreement) of 2.4% (− 5.4% to 10.1%), 6.9 mL/m2 (− 4.7 to 18.6 mL/m2), − 1.5 (− 8.3 to 5.2 mL/m2), and − 0.2 g/m2 (− 11.9 to 12.3 g/m2) for LV ejection fraction, end-diastolic volume index, end-systolic volume index, and mass index, respectively. LVSV by accelerated k-t SENSE presented good agreement with aortic flow. Interobserver and intraobserver variabilities for all LV parameters were also high. Conclusion The accelerated k-t SENSE CMR sequence is clinically feasible and accurately quantifies LV volumes, function, and mass, with short acquisition time and good image quality. |
| first_indexed | 2024-04-12T05:21:29Z |
| format | Article |
| id | doaj.art-9bcbfaa7bab84aaaa0fabd48328c2e9a |
| institution | Directory Open Access Journal |
| issn | 1869-4101 |
| language | English |
| last_indexed | 2024-04-12T05:21:29Z |
| publishDate | 2019-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Insights into Imaging |
| spelling | doaj.art-9bcbfaa7bab84aaaa0fabd48328c2e9a2022-12-22T03:46:26ZengSpringerOpenInsights into Imaging1869-41012019-06-011011810.1186/s13244-019-0750-6Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonanceAntonildes Nascimento Assuncao-Jr0Roberto Nery Dantas-Jr1Renata Margarida do Val2Priscilla Gianotto3Angela dos Santos Marin4Mark Golden5Marco Antonio Gutierrez6Jose Rodrigues Parga7Cesar Higa Nomura8Heart Institute (InCor), University of Sao Paulo Medical SchoolHeart Institute (InCor), University of Sao Paulo Medical SchoolHeart Institute (InCor), University of Sao Paulo Medical SchoolHeart Institute (InCor), University of Sao Paulo Medical SchoolCanon Medical Systems do BrasilCanon Medical Systems CorporationHeart Institute (InCor), University of Sao Paulo Medical SchoolHeart Institute (InCor), University of Sao Paulo Medical SchoolHeart Institute (InCor), University of Sao Paulo Medical SchoolAbstract Objectives To provide clinical validation of a recent 2D SENSE-based accelerated cardiovascular magnetic resonance (CMR) sequence (accelerated k-t SENSE), investigating whether this technique accurately quantifies left ventricle (LV) volumes, function, and mass as compared to 2D cine steady-state free precession (2D-SSFP). Methods Healthy volunteers (n = 16) and consecutive heart failure patients (n = 26) were scanned using a 1.5 T MRI system. Two LV short axis (SA) stacks were acquired: (1) accelerated k-t SENSE (5–6 breath-holds; temporal/spatial resolution: 37 ms/1.82 × 1.87 mm; acceleration factor = 4) and (2) standard 2D-SSFP (10–12 breath-holds; temporal/spatial resolution: 49 ms/1.67 × 1.87 mm, parallel imaging). Ascending aorta phase-contrast was performed on all volunteers as a reference to compare LV stroke volumes (LVSV) and validate the sequences. An image quality score for SA images was used, with lower scores indicating better quality (from 0 to 18). Results There was a high agreement between accelerated k-t SENSE and 2D-SSFP for LV measurements: bias (limits of agreement) of 2.4% (− 5.4% to 10.1%), 6.9 mL/m2 (− 4.7 to 18.6 mL/m2), − 1.5 (− 8.3 to 5.2 mL/m2), and − 0.2 g/m2 (− 11.9 to 12.3 g/m2) for LV ejection fraction, end-diastolic volume index, end-systolic volume index, and mass index, respectively. LVSV by accelerated k-t SENSE presented good agreement with aortic flow. Interobserver and intraobserver variabilities for all LV parameters were also high. Conclusion The accelerated k-t SENSE CMR sequence is clinically feasible and accurately quantifies LV volumes, function, and mass, with short acquisition time and good image quality.http://link.springer.com/article/10.1186/s13244-019-0750-6Cardiac function testCine magnetic resonance imagingCardiac imaging techniquesCongestive cardiomyopathiesVentricular ejection fraction |
| spellingShingle | Antonildes Nascimento Assuncao-Jr Roberto Nery Dantas-Jr Renata Margarida do Val Priscilla Gianotto Angela dos Santos Marin Mark Golden Marco Antonio Gutierrez Jose Rodrigues Parga Cesar Higa Nomura Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance Insights into Imaging Cardiac function test Cine magnetic resonance imaging Cardiac imaging techniques Congestive cardiomyopathies Ventricular ejection fraction |
| title | Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance |
| title_full | Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance |
| title_fullStr | Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance |
| title_full_unstemmed | Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance |
| title_short | Clinical evaluation of left ventricular function and morphology using an accelerated k-t sensitivity encoding method in cardiovascular magnetic resonance |
| title_sort | clinical evaluation of left ventricular function and morphology using an accelerated k t sensitivity encoding method in cardiovascular magnetic resonance |
| topic | Cardiac function test Cine magnetic resonance imaging Cardiac imaging techniques Congestive cardiomyopathies Ventricular ejection fraction |
| url | http://link.springer.com/article/10.1186/s13244-019-0750-6 |
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