HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave

HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave

There are conflicting reports on the effects of HIV on COVID-19. Here, we analyzed disease severity and immune cell changes during and after SARS-CoV-2 infection in 236 participants from South Africa, of which 39% were people living with HIV (PLWH), during the first and second (Beta dominated) infec...

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Bibliographic Details
Main Authors: Farina Karim, Inbal Gazy, Sandile Cele, Yenzekile Zungu, Robert Krause, Mallory Bernstein, Khadija Khan, Yashica Ganga, Hylton Rodel, Ntombifuthi Mthabela, Matilda Mazibuko, Daniel Muema, Dirhona Ramjit, Thumbi Ndung'u, Willem Hanekom, Bernadett Gosnell, COMMIT-KZN Team, Richard J Lessells, Emily B Wong, Tulio de Oliveira, Mahomed-Yunus S Moosa, Gil Lustig, Alasdair Leslie, Henrik Kløverpris, Alex Sigal
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
SARS-CoV-2
COVID-19
HIV
antiretroviral therapy
beta variant
Online Access:https://elifesciences.org/articles/67397

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