Prognostic value of integrin αV expression and localization pattern in invasive breast carcinomas

Prognostic value of integrin αV expression and localization pattern in invasive breast carcinomas

Invasion of surrounding stroma is an early event in breast cancer metastatic progression, and involves loss of cell polarity, loss of myoepithelial layer, epithelial-mesenchymal transition (EMT) and remodeling of the extracellular matrix (ECM). Integrins are transmembrane receptors responsible for c...

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Bibliographic Details
Main Authors: Otto Luiz Dutra Cerqueira, Mayara Carolline Silva Botelho, Ana Paula Zen Petisco Fiore, Cynthia Aparecida Bueno de Toledo Osório, Rebeka Tomasin, Mauro César Cafundó Morais, Rossana Verónica Mendoza López, Elaine Cristina Cardoso, Santiago Andres Vilella-Arias, Eduardo Moraes Reis, Alexandre Bruni-Cardoso
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Breast cancer
Tissue microarray
Integrin αV
3D cell culture
Tumor stroma
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558622000306

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