Histiocytoid Sweet syndrome: Report of two cases and review of the literature
Histiocytoid Sweet syndrome (SS) is a rare inflammatory disease that has recently been described as a variant of classic SS. Histopathologically, histiocytoid SS is characterized by papillary dermal edema with infiltration of histiocyte-like cells into the upper dermis. These microscopic features ma...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-06-01
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| Series: | Dermatologica Sinica |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1027811711001066 |
| _version_ | 1818355963244052480 |
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| author | Ching-Fu Huang Bai-Yao Wu Fang-Yih Liaw Wei-Ming Wang Chien-Ping Chiang |
| author_facet | Ching-Fu Huang Bai-Yao Wu Fang-Yih Liaw Wei-Ming Wang Chien-Ping Chiang |
| author_sort | Ching-Fu Huang |
| collection | DOAJ |
| description | Histiocytoid Sweet syndrome (SS) is a rare inflammatory disease that has recently been described as a variant of classic SS. Histopathologically, histiocytoid SS is characterized by papillary dermal edema with infiltration of histiocyte-like cells into the upper dermis. These microscopic features may be similar to those of leukemia cutis, which involves infiltration of malignant blasts into the dermis. However, the treatment and clinical prognosis of these two conditions are quite different. Here, we report the case of two Taiwanese patients with histiocytoid SS. Interestingly, one of the patients had a history of myelodysplastic syndrome and was initially considered to have ongoing leukemic transformation with concomitant leukemia cutis. Finally, the patient was diagnosed with histiocytoid SS based on histological findings, and both patients were successfully treated with low-dose oral corticosteroids. |
| first_indexed | 2024-12-13T19:49:40Z |
| format | Article |
| id | doaj.art-9bd2fe7f09ff41339066d9800d6f0ab7 |
| institution | Directory Open Access Journal |
| issn | 1027-8117 |
| language | English |
| last_indexed | 2024-12-13T19:49:40Z |
| publishDate | 2012-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dermatologica Sinica |
| spelling | doaj.art-9bd2fe7f09ff41339066d9800d6f0ab72022-12-21T23:33:27ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172012-06-01302717410.1016/j.dsi.2011.10.003Histiocytoid Sweet syndrome: Report of two cases and review of the literatureChing-Fu Huang0Bai-Yao Wu1Fang-Yih Liaw2Wei-Ming Wang3Chien-Ping Chiang4Department of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROCDepartment of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROCDepartment of Family and Community Health, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROCDepartment of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROCDepartment of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROCHistiocytoid Sweet syndrome (SS) is a rare inflammatory disease that has recently been described as a variant of classic SS. Histopathologically, histiocytoid SS is characterized by papillary dermal edema with infiltration of histiocyte-like cells into the upper dermis. These microscopic features may be similar to those of leukemia cutis, which involves infiltration of malignant blasts into the dermis. However, the treatment and clinical prognosis of these two conditions are quite different. Here, we report the case of two Taiwanese patients with histiocytoid SS. Interestingly, one of the patients had a history of myelodysplastic syndrome and was initially considered to have ongoing leukemic transformation with concomitant leukemia cutis. Finally, the patient was diagnosed with histiocytoid SS based on histological findings, and both patients were successfully treated with low-dose oral corticosteroids.http://www.sciencedirect.com/science/article/pii/S1027811711001066histiocytoid Sweet syndromehistological featuresinflammatory disease |
| spellingShingle | Ching-Fu Huang Bai-Yao Wu Fang-Yih Liaw Wei-Ming Wang Chien-Ping Chiang Histiocytoid Sweet syndrome: Report of two cases and review of the literature Dermatologica Sinica histiocytoid Sweet syndrome histological features inflammatory disease |
| title | Histiocytoid Sweet syndrome: Report of two cases and review of the literature |
| title_full | Histiocytoid Sweet syndrome: Report of two cases and review of the literature |
| title_fullStr | Histiocytoid Sweet syndrome: Report of two cases and review of the literature |
| title_full_unstemmed | Histiocytoid Sweet syndrome: Report of two cases and review of the literature |
| title_short | Histiocytoid Sweet syndrome: Report of two cases and review of the literature |
| title_sort | histiocytoid sweet syndrome report of two cases and review of the literature |
| topic | histiocytoid Sweet syndrome histological features inflammatory disease |
| url | http://www.sciencedirect.com/science/article/pii/S1027811711001066 |
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