Bio-Inspired Polymersome Nanoreactors
Abstract: Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response to external triggers. Here...
| Main Authors: | , , |
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2019-02-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://www.chimia.ch/chimia/article/view/1180 |
| _version_ | 1818295731419611136 |
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| author | Omar Rifaie-Graham Edward A. Apebende Nico Bruns |
| author_facet | Omar Rifaie-Graham Edward A. Apebende Nico Bruns |
| author_sort | Omar Rifaie-Graham |
| collection | DOAJ |
| description |
Abstract: Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response to external triggers.
Here we review our efforts to implement these concepts into artificial nanoreactors. Block copolymer vesicles (polymersomes) for laccase-catalyzed oxidations as well as a generally applicable permeabilization method for polymersome membranes are highlighted. Moreover, polymersome nanoreactors
that can be switched on by visible light and that immediately return to their off state in the dark are reviewed. These systems have the potential to create bio-inspired catalytic systems, e.g. to orchestrate reaction cascades.
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| first_indexed | 2024-12-13T03:52:18Z |
| format | Article |
| id | doaj.art-9bd394a6875b4f59afeea6ae841ef4d2 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-12-13T03:52:18Z |
| publishDate | 2019-02-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-9bd394a6875b4f59afeea6ae841ef4d22022-12-22T00:00:41ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242019-02-01731-210.2533/chimia.2019.21Bio-Inspired Polymersome NanoreactorsOmar Rifaie-GrahamEdward A. ApebendeNico Bruns Abstract: Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response to external triggers. Here we review our efforts to implement these concepts into artificial nanoreactors. Block copolymer vesicles (polymersomes) for laccase-catalyzed oxidations as well as a generally applicable permeabilization method for polymersome membranes are highlighted. Moreover, polymersome nanoreactors that can be switched on by visible light and that immediately return to their off state in the dark are reviewed. These systems have the potential to create bio-inspired catalytic systems, e.g. to orchestrate reaction cascades. https://www.chimia.ch/chimia/article/view/1180Amphiphilic block copolymersBiocatalysisNanoreactorsTransient out-of-equilibrium systemsVesicles |
| spellingShingle | Omar Rifaie-Graham Edward A. Apebende Nico Bruns Bio-Inspired Polymersome Nanoreactors CHIMIA Amphiphilic block copolymers Biocatalysis Nanoreactors Transient out-of-equilibrium systems Vesicles |
| title | Bio-Inspired Polymersome Nanoreactors |
| title_full | Bio-Inspired Polymersome Nanoreactors |
| title_fullStr | Bio-Inspired Polymersome Nanoreactors |
| title_full_unstemmed | Bio-Inspired Polymersome Nanoreactors |
| title_short | Bio-Inspired Polymersome Nanoreactors |
| title_sort | bio inspired polymersome nanoreactors |
| topic | Amphiphilic block copolymers Biocatalysis Nanoreactors Transient out-of-equilibrium systems Vesicles |
| url | https://www.chimia.ch/chimia/article/view/1180 |
| work_keys_str_mv | AT omarrifaiegraham bioinspiredpolymersomenanoreactors AT edwardaapebende bioinspiredpolymersomenanoreactors AT nicobruns bioinspiredpolymersomenanoreactors |