The First-in-Human Whole-Body Dynamic Pharmacokinetics Study of Aptamer

Serving as targeting ligands, aptamers have shown promise in precision medicine. However, the lack of knowledge of the biosafety and metabolism patterns in the human body largely impeded aptamers’ clinical translation. To bridge this gap, here we report the first-in-human pharmacokinetics study of p...

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Bibliographic Details
Main Authors: Ding Ding, Haitao Zhao, Dali Wei, Qinglai Yang, Cai Yang, Ruowen Wang, Yumei Chen, Lianghua Li, Shuxian An, Qian Xia, Gang Huang, Jianjun Liu, Zeyu Xiao, Weihong Tan
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0126