Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high p...
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Elsevier
2014-01-01
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Series: | Journal of Functional Foods |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464613003010 |
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author | Eun Ae Yu Gon-Sup Kim Sung Woo Jeong Semin Park Soo Jung Lee Jae Hoon Kim Won Sup Lee Ki-Min Bark Jong Sung Jin Sung Chul Shin |
author_facet | Eun Ae Yu Gon-Sup Kim Sung Woo Jeong Semin Park Soo Jung Lee Jae Hoon Kim Won Sup Lee Ki-Min Bark Jong Sung Jin Sung Chul Shin |
author_sort | Eun Ae Yu |
collection | DOAJ |
description | The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) and compared to the literature data. Flavanones, flavones, and the coumarin derivative were validated in terms of hesperetin, nobiletin, and coumarin levels, respectively, and quantified using the validated methods. The total concentration of the components was 4212.6 ± 37.0 mg/kg fresh peel. Naringin (1) was the most dominant component, followed by hesperidin (2). Antioxidant abilities in terms of DPPH·, ABTS·+ and reducing power were evaluated between 50 and 1000 mg/L. The antioxidant activities of the flavonoids increased in a dose-dependent manner. |
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issn | 1756-4646 |
language | English |
last_indexed | 2024-12-14T03:18:47Z |
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series | Journal of Functional Foods |
spelling | doaj.art-9bd3c00d37f4426c850174970bdaabf32022-12-21T23:19:04ZengElsevierJournal of Functional Foods1756-46462014-01-016637642Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effectEun Ae Yu0Gon-Sup Kim1Sung Woo Jeong2Semin Park3Soo Jung Lee4Jae Hoon Kim5Won Sup Lee6Ki-Min Bark7Jong Sung Jin8Sung Chul Shin9Department of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Jinju 660-701, Republic of KoreaDepartment of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaDepartment of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaDepartment of Food and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaFaculty of Biotechnology, Citrus Genetic Resources Bank, College of Applied Life Science, Jeju National University, SARI, Jeju 690-756, Republic of KoreaDepartment of Internal Medicine, Institute of Health Sciences and Gyeongnam Regional Cancer Center, Gyeongsang National University, Jinju 660-702, Republic of Korea; Corresponding authors. Tel.: +82 55 750 8733 (W.S. Lee). Tel.: +82 55 772 1484; fax: +82 55 772 1489 (S.C. Shin).Department of Chemical Education and Research Institute of Life Sciences, Gyeongsang National University, Jinju 660-701, Republic of KoreaDivision of High Technology Materials Research, Busan Center, Korea Basic Science Institute (KBSI), Busan 618-230, Republic of KoreaDepartment of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of Korea; Corresponding authors. Tel.: +82 55 750 8733 (W.S. Lee). Tel.: +82 55 772 1484; fax: +82 55 772 1489 (S.C. Shin).The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) and compared to the literature data. Flavanones, flavones, and the coumarin derivative were validated in terms of hesperetin, nobiletin, and coumarin levels, respectively, and quantified using the validated methods. The total concentration of the components was 4212.6 ± 37.0 mg/kg fresh peel. Naringin (1) was the most dominant component, followed by hesperidin (2). Antioxidant abilities in terms of DPPH·, ABTS·+ and reducing power were evaluated between 50 and 1000 mg/L. The antioxidant activities of the flavonoids increased in a dose-dependent manner.http://www.sciencedirect.com/science/article/pii/S1756464613003010Citrus tangerinaLiquid chromatography–tandem mass spectrometryFlavonoidsPolymethoxyflavonesAntioxidant activity |
spellingShingle | Eun Ae Yu Gon-Sup Kim Sung Woo Jeong Semin Park Soo Jung Lee Jae Hoon Kim Won Sup Lee Ki-Min Bark Jong Sung Jin Sung Chul Shin Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect Journal of Functional Foods Citrus tangerina Liquid chromatography–tandem mass spectrometry Flavonoids Polymethoxyflavones Antioxidant activity |
title | Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect |
title_full | Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect |
title_fullStr | Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect |
title_full_unstemmed | Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect |
title_short | Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect |
title_sort | flavonoid profile and biological activity of korean citrus varieties ii pyunkyul citrus tangerina hort ex tanaka and overall contribution of its flavonoids to antioxidant effect |
topic | Citrus tangerina Liquid chromatography–tandem mass spectrometry Flavonoids Polymethoxyflavones Antioxidant activity |
url | http://www.sciencedirect.com/science/article/pii/S1756464613003010 |
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