Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect

The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high p...

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Main Authors: Eun Ae Yu, Gon-Sup Kim, Sung Woo Jeong, Semin Park, Soo Jung Lee, Jae Hoon Kim, Won Sup Lee, Ki-Min Bark, Jong Sung Jin, Sung Chul Shin
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464613003010
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author Eun Ae Yu
Gon-Sup Kim
Sung Woo Jeong
Semin Park
Soo Jung Lee
Jae Hoon Kim
Won Sup Lee
Ki-Min Bark
Jong Sung Jin
Sung Chul Shin
author_facet Eun Ae Yu
Gon-Sup Kim
Sung Woo Jeong
Semin Park
Soo Jung Lee
Jae Hoon Kim
Won Sup Lee
Ki-Min Bark
Jong Sung Jin
Sung Chul Shin
author_sort Eun Ae Yu
collection DOAJ
description The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) and compared to the literature data. Flavanones, flavones, and the coumarin derivative were validated in terms of hesperetin, nobiletin, and coumarin levels, respectively, and quantified using the validated methods. The total concentration of the components was 4212.6 ± 37.0 mg/kg fresh peel. Naringin (1) was the most dominant component, followed by hesperidin (2). Antioxidant abilities in terms of DPPH·, ABTS·+ and reducing power were evaluated between 50 and 1000 mg/L. The antioxidant activities of the flavonoids increased in a dose-dependent manner.
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spelling doaj.art-9bd3c00d37f4426c850174970bdaabf32022-12-21T23:19:04ZengElsevierJournal of Functional Foods1756-46462014-01-016637642Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effectEun Ae Yu0Gon-Sup Kim1Sung Woo Jeong2Semin Park3Soo Jung Lee4Jae Hoon Kim5Won Sup Lee6Ki-Min Bark7Jong Sung Jin8Sung Chul Shin9Department of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaResearch Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University, Jinju 660-701, Republic of KoreaDepartment of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaDepartment of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaDepartment of Food and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University, Jinju 660-701, Republic of KoreaFaculty of Biotechnology, Citrus Genetic Resources Bank, College of Applied Life Science, Jeju National University, SARI, Jeju 690-756, Republic of KoreaDepartment of Internal Medicine, Institute of Health Sciences and Gyeongnam Regional Cancer Center, Gyeongsang National University, Jinju 660-702, Republic of Korea; Corresponding authors. Tel.: +82 55 750 8733 (W.S. Lee). Tel.: +82 55 772 1484; fax: +82 55 772 1489 (S.C. Shin).Department of Chemical Education and Research Institute of Life Sciences, Gyeongsang National University, Jinju 660-701, Republic of KoreaDivision of High Technology Materials Research, Busan Center, Korea Basic Science Institute (KBSI), Busan 618-230, Republic of KoreaDepartment of Chemistry and Research Institute of Life Science, Gyeongsang National University, Jinju 660-701, Republic of Korea; Corresponding authors. Tel.: +82 55 750 8733 (W.S. Lee). Tel.: +82 55 772 1484; fax: +82 55 772 1489 (S.C. Shin).The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) and compared to the literature data. Flavanones, flavones, and the coumarin derivative were validated in terms of hesperetin, nobiletin, and coumarin levels, respectively, and quantified using the validated methods. The total concentration of the components was 4212.6 ± 37.0 mg/kg fresh peel. Naringin (1) was the most dominant component, followed by hesperidin (2). Antioxidant abilities in terms of DPPH·, ABTS·+ and reducing power were evaluated between 50 and 1000 mg/L. The antioxidant activities of the flavonoids increased in a dose-dependent manner.http://www.sciencedirect.com/science/article/pii/S1756464613003010Citrus tangerinaLiquid chromatography–tandem mass spectrometryFlavonoidsPolymethoxyflavonesAntioxidant activity
spellingShingle Eun Ae Yu
Gon-Sup Kim
Sung Woo Jeong
Semin Park
Soo Jung Lee
Jae Hoon Kim
Won Sup Lee
Ki-Min Bark
Jong Sung Jin
Sung Chul Shin
Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
Journal of Functional Foods
Citrus tangerina
Liquid chromatography–tandem mass spectrometry
Flavonoids
Polymethoxyflavones
Antioxidant activity
title Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
title_full Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
title_fullStr Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
title_full_unstemmed Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
title_short Flavonoid profile and biological activity of Korean citrus varieties (II): Pyunkyul (Citrus tangerina Hort. ex Tanaka) and overall contribution of its flavonoids to antioxidant effect
title_sort flavonoid profile and biological activity of korean citrus varieties ii pyunkyul citrus tangerina hort ex tanaka and overall contribution of its flavonoids to antioxidant effect
topic Citrus tangerina
Liquid chromatography–tandem mass spectrometry
Flavonoids
Polymethoxyflavones
Antioxidant activity
url http://www.sciencedirect.com/science/article/pii/S1756464613003010
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