Doxorubicin Dose-Dependent Impact on Physiological Balance—A Holistic Approach in a Rat Model

Doxorubicin Dose-Dependent Impact on Physiological Balance—A Holistic Approach in a Rat Model

Doxorubicin (DOX) is commonly used in several chemotherapies to treat various cancers, but it is known to cause cardiotoxicity and cardiac symptoms. Autonomic dysfunction is thought to contribute to the cardiotoxic effects of DOX, but the specific dose required to disrupt homeostatic processes is st...

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Bibliographic Details
Main Authors:	Ana I. Afonso, Ângela Amaro-Leal, Filipa Machado, Isabel Rocha, Vera Geraldes
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Series:	Biology
Subjects:	doxorubicin dosage autonomic nervous system HRV physiological parameters
Online Access:	https://www.mdpi.com/2079-7737/12/7/1031

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