Data Fusion Techniques for the Integration of Multi-Domain Genomic Data from Uveal Melanoma

Data Fusion Techniques for the Integration of Multi-Domain Genomic Data from Uveal Melanoma

Uveal melanoma (UM) is a rare cancer that is well characterized at the molecular level. Two to four classes have been identified by the analyses of gene expression (mRNA, ncRNA), DNA copy number, DNA-methylation and somatic mutations yet no factual integration of these data has been reported. We the...

Full description

Bibliographic Details
Main Authors: Max Pfeffer, André Uschmajew, Adriana Amaro, Ulrich Pfeffer
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
dna-methylation
copy number alteration
gene expression profile
metastasis
tumor classification
tumor subtypes
data fusion
singular value decomposition
constrained matrix factorization
similarity network fusion
Online Access:https://www.mdpi.com/2072-6694/11/10/1434

Internet

https://www.mdpi.com/2072-6694/11/10/1434

Similar Items