Starve Cancer Cells of Glutamine: Break the Spell or Make a Hungry Monster?

Starve Cancer Cells of Glutamine: Break the Spell or Make a Hungry Monster?

Distinct from normal differentiated tissues, cancer cells reprogram nutrient uptake and utilization to accommodate their elevated demands for biosynthesis and energy production. A hallmark of these types of reprogramming is the increased utilization of, and dependency on glutamine, a nonessential am...

Full description

Bibliographic Details
Main Authors: Jie Jiang, Sankalp Srivastava, Ji Zhang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
glutamine
biosynthesis
amino acid starvation
adaptation
asparagine
aspartate
arginine
glutaminase
Online Access:https://www.mdpi.com/2072-6694/11/6/804

Similar Items

Similar Items