Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss
Effect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damag...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2019-02-01
|
| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6673 |
| _version_ | 1819038602878779392 |
|---|---|
| author | O. P. Matviychuk A. V. Matviychuk A. V. Taran |
| author_facet | O. P. Matviychuk A. V. Matviychuk A. V. Taran |
| author_sort | O. P. Matviychuk |
| collection | DOAJ |
| description | Effect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damage resulting in acute renal failure (ARF). As a result of the application of benofilin its ability is established to prevent the death of animals in the first day of the experiment. By the ability to prevent impaired kidney function in rats benofilin exceeds the effect of the hofitol. |
| first_indexed | 2024-12-21T08:39:56Z |
| format | Article |
| id | doaj.art-9bd8bd55202e4cf9995ab9e2697fc868 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-21T08:39:56Z |
| publishDate | 2019-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-9bd8bd55202e4cf9995ab9e2697fc8682022-12-21T19:09:59ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-02-019249349910.5281/zenodo.25894445952Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic lossO. P. Matviychuk0A. V. Matviychuk1A. V. Taran2National University of PharmacyNational University of PharmacyNational University of PharmacyEffect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damage resulting in acute renal failure (ARF). As a result of the application of benofilin its ability is established to prevent the death of animals in the first day of the experiment. By the ability to prevent impaired kidney function in rats benofilin exceeds the effect of the hofitol.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6673benofilin, acute kidney damage, diuretic, nephroprotective activity, rats |
| spellingShingle | O. P. Matviychuk A. V. Matviychuk A. V. Taran Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss Journal of Education, Health and Sport benofilin, acute kidney damage, diuretic, nephroprotective activity, rats |
| title | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_full | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_fullStr | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_full_unstemmed | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_short | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_sort | expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| topic | benofilin, acute kidney damage, diuretic, nephroprotective activity, rats |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6673 |
| work_keys_str_mv | AT opmatviychuk expermentalresearchoftheeffectsofbenofilinonthefunctionalrenalfunctionintheevalutionofethyleneglycoltoxicloss AT avmatviychuk expermentalresearchoftheeffectsofbenofilinonthefunctionalrenalfunctionintheevalutionofethyleneglycoltoxicloss AT avtaran expermentalresearchoftheeffectsofbenofilinonthefunctionalrenalfunctionintheevalutionofethyleneglycoltoxicloss |