Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus

AimThe aim of the present study was to investigate levels of some biochemical and whole blood count parameters and plasma viscosity in women with gestational diabetes mellitus (GDM) compared to healthy pregnant and healthy, non-pregnant women, and to evaluate the relationships between plasma viscosi...

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Main Authors: Birsen Aydemir, Ali Rıza Kızıler, F.Behice Cinemre, Hakan Cinemre, Abdullah Tüten, Mahmut Öncül, A. Serdar Açıkgöz, Gönül Gürol
Format: Article
Language:English
Published: Galenos Yayincilik 2015-04-01
Series:Namık Kemal Tıp Dergisi
Subjects:
Online Access: http://namikkemalmedj.com/archives/archive-detail/article-preview/relation-between-plazma-viscosity-and-some-biochem/40475
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author Birsen Aydemir
Ali Rıza Kızıler
F.Behice Cinemre
Hakan Cinemre
Abdullah Tüten
Mahmut Öncül
A. Serdar Açıkgöz
Gönül Gürol
author_facet Birsen Aydemir
Ali Rıza Kızıler
F.Behice Cinemre
Hakan Cinemre
Abdullah Tüten
Mahmut Öncül
A. Serdar Açıkgöz
Gönül Gürol
author_sort Birsen Aydemir
collection DOAJ
description AimThe aim of the present study was to investigate levels of some biochemical and whole blood count parameters and plasma viscosity in women with gestational diabetes mellitus (GDM) compared to healthy pregnant and healthy, non-pregnant women, and to evaluate the relationships between plasma viscosity.Material-MethodsThe patients consisted of 27 pregnant with GDM. The control groups consisted of 25 healthy pregnant and 24 healthy non-pregnant women. Blood glucose, insulin, glycosylated hemoglobin (HbA1c), total cholesterol, triacylglycerol, LDL-cholesterol, HDL-cholesterol, total protein, albumin, HbA1c, Hct, Hb, PLT, MPV were measured by auto-analyzer. Also, plasma viscosity levels were measured by capillary viscometer.ResultsThe levels of total protein, albumin, blood glucose, insulin, HOMAIR, HBA1c, total cholesterol, LDL-Cholesterol, HDL-Cholesterol and plazma viscosity in women with GDM group were found higher than those in healthy pregnant and non-pregnant women groups. In addition, the levels of triacylglycerol were significantly higher in GDM pregnants than those in the healthy pregnant women. There were significant positive correlations between plasma viscosity and total cholesterol levels of GDM patients. Additionally, there were significant positive correlations between plasma viscosity and LDL-cholesterol levels.ConclusionPlasma viscosity may contribute to useful information in early diagnosis and treatment, prevention of progression in GDM patients. It should be considered as an important parameter in clinical terms to ensure healthy fetal development.
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spelling doaj.art-9bdaf8afb31a40c7af178054527fe60a2023-02-15T16:16:41ZengGalenos YayincilikNamık Kemal Tıp Dergisi2587-02622015-04-013161413049054Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes MellitusBirsen Aydemir0Ali Rıza Kızıler1F.Behice Cinemre2Hakan Cinemre3Abdullah Tüten4Mahmut Öncül5A. Serdar Açıkgöz6Gönül Gürol7 Sakarya Üniversitesi Tıp Fakültesi, Biyofizik Anabilim Dalı, Sakarya Namık Kemal Üniversitesi Tıp Fakültesi, Biyofizik Anabilim Dalı, Tekirdağ Sakarya Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı, Sakarya Sakarya Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Sakarya İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul Sakarya Üniversitesi Tıp Fakültesi, Fizyoloji Anabilim Dalı, Sakarya AimThe aim of the present study was to investigate levels of some biochemical and whole blood count parameters and plasma viscosity in women with gestational diabetes mellitus (GDM) compared to healthy pregnant and healthy, non-pregnant women, and to evaluate the relationships between plasma viscosity.Material-MethodsThe patients consisted of 27 pregnant with GDM. The control groups consisted of 25 healthy pregnant and 24 healthy non-pregnant women. Blood glucose, insulin, glycosylated hemoglobin (HbA1c), total cholesterol, triacylglycerol, LDL-cholesterol, HDL-cholesterol, total protein, albumin, HbA1c, Hct, Hb, PLT, MPV were measured by auto-analyzer. Also, plasma viscosity levels were measured by capillary viscometer.ResultsThe levels of total protein, albumin, blood glucose, insulin, HOMAIR, HBA1c, total cholesterol, LDL-Cholesterol, HDL-Cholesterol and plazma viscosity in women with GDM group were found higher than those in healthy pregnant and non-pregnant women groups. In addition, the levels of triacylglycerol were significantly higher in GDM pregnants than those in the healthy pregnant women. There were significant positive correlations between plasma viscosity and total cholesterol levels of GDM patients. Additionally, there were significant positive correlations between plasma viscosity and LDL-cholesterol levels.ConclusionPlasma viscosity may contribute to useful information in early diagnosis and treatment, prevention of progression in GDM patients. It should be considered as an important parameter in clinical terms to ensure healthy fetal development. http://namikkemalmedj.com/archives/archive-detail/article-preview/relation-between-plazma-viscosity-and-some-biochem/40475 gestational diabetes mellitusplasma viscositylipit profiletotal proteinblood glucoseinsulinhematocrithemoglobinplateletsmean platelet volume
spellingShingle Birsen Aydemir
Ali Rıza Kızıler
F.Behice Cinemre
Hakan Cinemre
Abdullah Tüten
Mahmut Öncül
A. Serdar Açıkgöz
Gönül Gürol
Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
Namık Kemal Tıp Dergisi
gestational diabetes mellitus
plasma viscosity
lipit profile
total protein
blood glucose
insulin
hematocrit
hemoglobin
platelets
mean platelet volume
title Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
title_full Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
title_fullStr Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
title_full_unstemmed Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
title_short Relation Between Plazma Viscosity and Some Biochemical Parameters in Women with Gestational Diabetes Mellitus
title_sort relation between plazma viscosity and some biochemical parameters in women with gestational diabetes mellitus
topic gestational diabetes mellitus
plasma viscosity
lipit profile
total protein
blood glucose
insulin
hematocrit
hemoglobin
platelets
mean platelet volume
url http://namikkemalmedj.com/archives/archive-detail/article-preview/relation-between-plazma-viscosity-and-some-biochem/40475
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