Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males
Abstract This study investigated the combined effects of 12 weeks of high-intensity interval training (HIIT) and spirulina supplementation on adipokine levels, insulin resistance, anthropometric indices, and cardiorespiratory fitness in 44 obese males (aged 25–40 years). The participants were random...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | Nutrition & Metabolism |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12986-024-00785-0 |
| _version_ | 1797266921516695552 |
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| author | Maryam Delfan Ayoub Saeidi Rashmi Supriya Kurt A Escobar Ismail Laher Katie M. Heinrich Katja Weiss Beat Knechtle Hassane Zouhal |
| author_facet | Maryam Delfan Ayoub Saeidi Rashmi Supriya Kurt A Escobar Ismail Laher Katie M. Heinrich Katja Weiss Beat Knechtle Hassane Zouhal |
| author_sort | Maryam Delfan |
| collection | DOAJ |
| description | Abstract This study investigated the combined effects of 12 weeks of high-intensity interval training (HIIT) and spirulina supplementation on adipokine levels, insulin resistance, anthropometric indices, and cardiorespiratory fitness in 44 obese males (aged 25–40 years). The participants were randomly assigned to one of four groups: control (CG), supplement (SG), training (TG), or training plus supplement (TSG). The intervention involved daily administration of either spirulina or a placebo and HIIT three times a week for the training groups. Anthropometric indices, HOMA-IR, VO2peak, and circulating adipokines (asprosin and lipocalin2, omentin-1, irisin, and spexin) were measured before and after the 12-week intervention. Post-intervention analysis indicated differences between the CG and the three interventional groups for body weight, fat-free mass (FFM), percent body fat (%BF), HOMA-IR, and adipokine levels (p < 0.05). TG and SG participants had increased VO2peak (p < 0.05). Spirulina supplementation with HIIT increased VO2peak, omentin-1, irisin, and spexin, while causing decreases in lipocalin-2 and asprosin levels and improvements in body composition (weight, %fat), BMI, and HOMA-IR. Notably, the combination of spirulina and HIIT produced more significant changes in circulating adipokines and cardiometabolic health in obese males compared to either supplementation or HIIT alone (p < 0.05). These findings highlight the synergistic benefits of combining spirulina supplementation with HIIT, showcasing their potential in improving various health parameters and addressing obesity-related concerns in a comprehensive manner. |
| first_indexed | 2024-04-25T01:08:22Z |
| format | Article |
| id | doaj.art-9bddd7f9c87e4773abaf94d1d408377f |
| institution | Directory Open Access Journal |
| issn | 1743-7075 |
| language | English |
| last_indexed | 2024-04-25T01:08:22Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition & Metabolism |
| spelling | doaj.art-9bddd7f9c87e4773abaf94d1d408377f2024-03-10T12:07:31ZengBMCNutrition & Metabolism1743-70752024-03-0121111310.1186/s12986-024-00785-0Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese malesMaryam Delfan0Ayoub Saeidi1Rashmi Supriya2Kurt A Escobar3Ismail Laher4Katie M. Heinrich5Katja Weiss6Beat Knechtle7Hassane Zouhal8Department of Exercise Physiology, Faculty of Sport Sciences, Alzahra UniversityDepartment of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, University of KurdistanCentre for Health and Exercise Science Research, SPEH, Hong Kong Baptist UniversityDepartment of Kinesiology, California State UniversityDepartment of Anesthesiology, Pharmacology, and Therapeutics, Faculty of Medicine, University of British ColumbiaDepartment of Kinesiology, Kansas State UniversityInstitute of Primary Care, University of ZurichInstitute of Primary Care, University of ZurichUniv Rennes, M2S (Laboratoire MouvementAbstract This study investigated the combined effects of 12 weeks of high-intensity interval training (HIIT) and spirulina supplementation on adipokine levels, insulin resistance, anthropometric indices, and cardiorespiratory fitness in 44 obese males (aged 25–40 years). The participants were randomly assigned to one of four groups: control (CG), supplement (SG), training (TG), or training plus supplement (TSG). The intervention involved daily administration of either spirulina or a placebo and HIIT three times a week for the training groups. Anthropometric indices, HOMA-IR, VO2peak, and circulating adipokines (asprosin and lipocalin2, omentin-1, irisin, and spexin) were measured before and after the 12-week intervention. Post-intervention analysis indicated differences between the CG and the three interventional groups for body weight, fat-free mass (FFM), percent body fat (%BF), HOMA-IR, and adipokine levels (p < 0.05). TG and SG participants had increased VO2peak (p < 0.05). Spirulina supplementation with HIIT increased VO2peak, omentin-1, irisin, and spexin, while causing decreases in lipocalin-2 and asprosin levels and improvements in body composition (weight, %fat), BMI, and HOMA-IR. Notably, the combination of spirulina and HIIT produced more significant changes in circulating adipokines and cardiometabolic health in obese males compared to either supplementation or HIIT alone (p < 0.05). These findings highlight the synergistic benefits of combining spirulina supplementation with HIIT, showcasing their potential in improving various health parameters and addressing obesity-related concerns in a comprehensive manner.https://doi.org/10.1186/s12986-024-00785-0SpirulinaHigh-intensity interval trainingAdipokinesObesity |
| spellingShingle | Maryam Delfan Ayoub Saeidi Rashmi Supriya Kurt A Escobar Ismail Laher Katie M. Heinrich Katja Weiss Beat Knechtle Hassane Zouhal Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males Nutrition & Metabolism Spirulina High-intensity interval training Adipokines Obesity |
| title | Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males |
| title_full | Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males |
| title_fullStr | Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males |
| title_full_unstemmed | Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males |
| title_short | Enhancing cardiometabolic health: unveiling the synergistic effects of high-intensity interval training with spirulina supplementation on selected adipokines, insulin resistance, and anthropometric indices in obese males |
| title_sort | enhancing cardiometabolic health unveiling the synergistic effects of high intensity interval training with spirulina supplementation on selected adipokines insulin resistance and anthropometric indices in obese males |
| topic | Spirulina High-intensity interval training Adipokines Obesity |
| url | https://doi.org/10.1186/s12986-024-00785-0 |
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