Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil

ABSTRACT Objective: To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods: This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hos...

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Main Authors: Valéria Martins Soares, Isabela Neves de Almeida, Lida Jouca de Assis Figueredo, João Paulo Amaral Haddad, Camila Stefanie Fonseca de Oliveira, Wânia da Silva Carvalho, Silvana Spindola de Miranda
Format: Article
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia 2020-03-01
Series:Jornal Brasileiro de Pneumologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132020000200205&tlng=en
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author Valéria Martins Soares
Isabela Neves de Almeida
Lida Jouca de Assis Figueredo
João Paulo Amaral Haddad
Camila Stefanie Fonseca de Oliveira
Wânia da Silva Carvalho
Silvana Spindola de Miranda
author_facet Valéria Martins Soares
Isabela Neves de Almeida
Lida Jouca de Assis Figueredo
João Paulo Amaral Haddad
Camila Stefanie Fonseca de Oliveira
Wânia da Silva Carvalho
Silvana Spindola de Miranda
author_sort Valéria Martins Soares
collection DOAJ
description ABSTRACT Objective: To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods: This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospital, located in the city of Belo Horizonte, Brazil, between October of 2012 and October of 2014. We evaluated sociodemographic, behavioral, clinical, and radiological variables. The outcome considered to identify associations between tuberculosis and the explanatory variables was the treatment prescribed. To evaluate the associations between MDR-TB and the same explanatory variables, the change in MDR-TB treatment was considered. Results: The factors associated with tuberculosis were alcoholism, comorbidities, pulmonary cavitations, and a radiological pattern suggestive of tuberculosis. Cavitation and previous treatment for tuberculosis were associated with MDR-TB. Conclusions: Despite the significant progress made in the fight against tuberculosis, there is a need for coordinated actions that include social protection measures and patient support.
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spelling doaj.art-9be05ab8ab6f4b55b280f44fc9934f012022-12-22T04:12:30ZengSociedade Brasileira de Pneumologia e TisiologiaJornal Brasileiro de Pneumologia1806-37562020-03-0146210.36416/1806-3756/e20180386Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, BrazilValéria Martins Soareshttps://orcid.org/0000-0002-7976-0592Isabela Neves de Almeidahttps://orcid.org/0000-0001-6152-7648Lida Jouca de Assis Figueredohttps://orcid.org/0000-0001-5355-0784João Paulo Amaral Haddadhttps://orcid.org/0000-0003-2823-6288Camila Stefanie Fonseca de Oliveirahttps://orcid.org/0000-0002-5557-7267Wânia da Silva Carvalhohttps://orcid.org/0000-0002-2575-6352Silvana Spindola de Mirandahttps://orcid.org/0000-0001-7245-4472ABSTRACT Objective: To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods: This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospital, located in the city of Belo Horizonte, Brazil, between October of 2012 and October of 2014. We evaluated sociodemographic, behavioral, clinical, and radiological variables. The outcome considered to identify associations between tuberculosis and the explanatory variables was the treatment prescribed. To evaluate the associations between MDR-TB and the same explanatory variables, the change in MDR-TB treatment was considered. Results: The factors associated with tuberculosis were alcoholism, comorbidities, pulmonary cavitations, and a radiological pattern suggestive of tuberculosis. Cavitation and previous treatment for tuberculosis were associated with MDR-TB. Conclusions: Despite the significant progress made in the fight against tuberculosis, there is a need for coordinated actions that include social protection measures and patient support.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132020000200205&tlng=enTuberculosisRisk factorsTuberculosis, multidrug-resistant
spellingShingle Valéria Martins Soares
Isabela Neves de Almeida
Lida Jouca de Assis Figueredo
João Paulo Amaral Haddad
Camila Stefanie Fonseca de Oliveira
Wânia da Silva Carvalho
Silvana Spindola de Miranda
Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil
Jornal Brasileiro de Pneumologia
Tuberculosis
Risk factors
Tuberculosis, multidrug-resistant
title Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil
title_full Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil
title_fullStr Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil
title_full_unstemmed Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil
title_short Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil
title_sort factors associated with tuberculosis and multidrug resistant tuberculosis in patients treated at a tertiary referral hospital in the state of minas gerais brazil
topic Tuberculosis
Risk factors
Tuberculosis, multidrug-resistant
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132020000200205&tlng=en
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