Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspergillosis

Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspergillosis

BackgroundAspergillus fumigatus is a well-known opportunistic pathogen that causes a range of diseases including the often-fatal disease, invasive pulmonary aspergillosis (IPA), in immunocompromised populations. The severity of IPA is dependent on both host- and pathogen-derived signaling molecules...

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Bibliographic Details
Main Authors: Breanne N. Steffan, Dante Calise, Sung Chul Park, Mengyao Niu, Jun Yang, Bruce D. Hammock, MaryJane Jones, Chad Steele, Nancy P. Keller
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
Aspergillus fumigatus
GPR132
G2A
oxylipin
neutrophil
lung
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1173544/full

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