Adapting the Scar-in-a-Jar to Skin Fibrosis and Screening Traditional and Contemporary Anti-Fibrotic Therapies

Adapting the Scar-in-a-Jar to Skin Fibrosis and Screening Traditional and Contemporary Anti-Fibrotic Therapies

Skin fibrosis still constitutes an unmet clinical need. Although pharmacological strategies are at the forefront of scientific and technological research and innovation, their clinical translation is hindered by the poor predictive capacity of the currently available in vitro fibrosis models. Indeed...

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Bibliographic Details
Main Authors: João Q. Coentro, Ulrike May, Stuart Prince, John Zwaagstra, Olli Ritvos, Tero A.H. Järvinen, Dimitrios I. Zeugolis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
In vitro tools
drug testing
disease modelling
macromolecular crowding
fibrosis
anti-fibrotic molecules
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.756399/full

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