The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis

The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis

Abstract The role of zinc in hematopoiesis is currently unclear. Here, SLC39A10 (ZIP10) is identified as a key zinc transporter in hematopoiesis. The results show that in zebrafish, Slc39a10 is a key regulator of the response to zinc deficiency. Surprisingly, both slc39a10 mutant zebrafish and hemat...

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Bibliographic Details
Main Authors: Xuyan He, Chaodong Ge, Jun Xia, Zhidan Xia, Lu Zhao, Sicong Huang, Rong Wang, Jianwei Pan, Tao Cheng, Peng‐Fei Xu, Fudi Wang, Junxia Min
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
anemia
hematopoiesis
hematopoietic stem cells
HSPCs
SLC39A10
zinc homeostasis
Online Access:https://doi.org/10.1002/advs.202205345

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