Olmesartan-associated Enteropathy with Acute Kidney Injury

Olmesartan, a recently introduced angiotensin II receptor blocker for hypertension, has been reported to cause drug-induced small bowel enteropathy. The diagnosis of olmesartan-associated enteropathy (OAE) needs clinical suspicion and the exclusion of coeliac disease, as it mimics coeliac sprue. Onc...

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Main Authors: Moo Jin Kang, Kyung Hwa Min, Hyung Wook Kim, Su Bum Park, Dae Hwan Kang, Cheol Woong Choi, Su Jin Kim, Hyeong Seok Nam, Dae Gon Ryu
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2022-03-01
Series:The Korean Journal of Gastroenterology
Subjects:
Online Access:https://www.kjg.or.kr/journal/view.html?uid=5803&vmd=Full
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author Moo Jin Kang
Kyung Hwa Min
Hyung Wook Kim
Su Bum Park
Dae Hwan Kang
Cheol Woong Choi
Su Jin Kim
Hyeong Seok Nam
Dae Gon Ryu
author_facet Moo Jin Kang
Kyung Hwa Min
Hyung Wook Kim
Su Bum Park
Dae Hwan Kang
Cheol Woong Choi
Su Jin Kim
Hyeong Seok Nam
Dae Gon Ryu
author_sort Moo Jin Kang
collection DOAJ
description Olmesartan, a recently introduced angiotensin II receptor blocker for hypertension, has been reported to cause drug-induced small bowel enteropathy. The diagnosis of olmesartan-associated enteropathy (OAE) needs clinical suspicion and the exclusion of coeliac disease, as it mimics coeliac sprue. Once diagnosed, it can be completely cured with the discontinuation of olmesartan. However, due to the extremely low incidence of OAE in Korea, clinical suspicion and diagnosis may be a challenge. The authors report the first case of OAE presenting with chronic diarrhea and acute kidney injury in Korea.
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spelling doaj.art-9befd4e1296d42bca802ab742a8f1ace2023-09-27T01:54:49ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692022-03-0179313013410.4166/kjg.2022.007Olmesartan-associated Enteropathy with Acute Kidney InjuryMoo Jin Kang0Kyung Hwa Min1Hyung Wook Kim2https://orcid.org/0000-0002-2444-0591Su Bum Park3Dae Hwan Kang4Cheol Woong Choi5Su Jin Kim6Hyeong Seok Nam7Dae Gon Ryu8Department of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Internal Medicine, Pusan National University School of Medicine; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, KoreaOlmesartan, a recently introduced angiotensin II receptor blocker for hypertension, has been reported to cause drug-induced small bowel enteropathy. The diagnosis of olmesartan-associated enteropathy (OAE) needs clinical suspicion and the exclusion of coeliac disease, as it mimics coeliac sprue. Once diagnosed, it can be completely cured with the discontinuation of olmesartan. However, due to the extremely low incidence of OAE in Korea, clinical suspicion and diagnosis may be a challenge. The authors report the first case of OAE presenting with chronic diarrhea and acute kidney injury in Korea.https://www.kjg.or.kr/journal/view.html?uid=5803&vmd=Fullolmesartanenteropathydiarrheaacute kidney injury
spellingShingle Moo Jin Kang
Kyung Hwa Min
Hyung Wook Kim
Su Bum Park
Dae Hwan Kang
Cheol Woong Choi
Su Jin Kim
Hyeong Seok Nam
Dae Gon Ryu
Olmesartan-associated Enteropathy with Acute Kidney Injury
The Korean Journal of Gastroenterology
olmesartan
enteropathy
diarrhea
acute kidney injury
title Olmesartan-associated Enteropathy with Acute Kidney Injury
title_full Olmesartan-associated Enteropathy with Acute Kidney Injury
title_fullStr Olmesartan-associated Enteropathy with Acute Kidney Injury
title_full_unstemmed Olmesartan-associated Enteropathy with Acute Kidney Injury
title_short Olmesartan-associated Enteropathy with Acute Kidney Injury
title_sort olmesartan associated enteropathy with acute kidney injury
topic olmesartan
enteropathy
diarrhea
acute kidney injury
url https://www.kjg.or.kr/journal/view.html?uid=5803&vmd=Full
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AT kyunghwamin olmesartanassociatedenteropathywithacutekidneyinjury
AT hyungwookkim olmesartanassociatedenteropathywithacutekidneyinjury
AT subumpark olmesartanassociatedenteropathywithacutekidneyinjury
AT daehwankang olmesartanassociatedenteropathywithacutekidneyinjury
AT cheolwoongchoi olmesartanassociatedenteropathywithacutekidneyinjury
AT sujinkim olmesartanassociatedenteropathywithacutekidneyinjury
AT hyeongseoknam olmesartanassociatedenteropathywithacutekidneyinjury
AT daegonryu olmesartanassociatedenteropathywithacutekidneyinjury