Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease
<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is an inherited neurogenerative disease caused by an abnormal expansion of glutamine repeats in the huntingtin protein. There is currently no treatment to prevent the neurodegeneration caused by this de...
Main Authors: | Pineda Jose R, Pardo Raúl, Zala Diana, Yu Hua, Humbert Sandrine, Saudou Frédéric |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
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Series: | Molecular Brain |
Online Access: | http://www.molecularbrain.com/content/2/1/33 |
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