Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging
Abstract Background As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebellar diaschisis (CCD) was rarely discussed. In this study, the aim of o...
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| Format: | Article |
| Language: | English |
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BMC
2020-11-01
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| Series: | BMC Neuroscience |
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| Online Access: | http://link.springer.com/article/10.1186/s12868-020-00595-z |
| _version_ | 1818554824121122816 |
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| author | Juan Wang Li-Jun Pan Bin Zhou Jin-Yan Zu Yi-Xu Zhao Yang Li Wan-Qiu Zhu Lei Li Jian-Rong Xu Zeng-Ai Chen |
| author_facet | Juan Wang Li-Jun Pan Bin Zhou Jin-Yan Zu Yi-Xu Zhao Yang Li Wan-Qiu Zhu Lei Li Jian-Rong Xu Zeng-Ai Chen |
| author_sort | Juan Wang |
| collection | DOAJ |
| description | Abstract Background As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebellar diaschisis (CCD) was rarely discussed. In this study, the aim of our study was to assess the performance of ASL-MRI in the detection of crossed cerebellar diaschisis after stroke in compared with single-photon emission CT (SPECT). Results 17 of 51(33.3%) patients revealed CCD phenomenon by the SPECT method. In CCD-positive group, CBF ASL of ipsilateral cerebellar were significantly increased compared with contralateral cerebellar (p < 0.0001) while no significant differences (p = 0.063, > 0.001) in the CCD-negative group. Positive correlation was detected between admission National institute of health stroke scale (NIHSS) and asymmetry index of SPECT (AI SPECT ) (r = 0.351, p = 0.011), AI ASL (r = 0.372, p = 0.007); infract volume and AI SPECT (r = 0.443, p = 0.001), AI ASL (r = 0.426, p = 0.002). Significant correlation was also found between cerebral blood flow of SPECT (CBF SPECT ) and CBF ASL , AI SPECT and AI ASL (r = 0.204, p = 0.04; r = 0.467, p = 0.001, respectively). Furthermore, the area under the receiver operating characteristic (ROC) curve value of AI ASL was 0.829. Conclusions CBF derived from ASL-MRI could be valuable for assessment of CCD in supratentorial stroke patients. Additionally, CCD was significantly associated with larger ischemic volume and higher initial NIHSS score. |
| first_indexed | 2024-12-12T09:45:09Z |
| format | Article |
| id | doaj.art-9bff736b283f4a2b90a2c200b9a3a016 |
| institution | Directory Open Access Journal |
| issn | 1471-2202 |
| language | English |
| last_indexed | 2024-12-12T09:45:09Z |
| publishDate | 2020-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neuroscience |
| spelling | doaj.art-9bff736b283f4a2b90a2c200b9a3a0162022-12-22T00:28:25ZengBMCBMC Neuroscience1471-22022020-11-012111710.1186/s12868-020-00595-zCrossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imagingJuan Wang0Li-Jun Pan1Bin Zhou2Jin-Yan Zu3Yi-Xu Zhao4Yang Li5Wan-Qiu Zhu6Lei Li7Jian-Rong Xu8Zeng-Ai Chen9Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital South Campus, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital South Campus, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityAbstract Background As a noninvasive perfusion-weighted MRI technique, arterial spin-labeling (ASL) was becoming increasingly used to evaluate cerebral hemodynamics in many studies. The relation between ASL-MRI and crossed cerebellar diaschisis (CCD) was rarely discussed. In this study, the aim of our study was to assess the performance of ASL-MRI in the detection of crossed cerebellar diaschisis after stroke in compared with single-photon emission CT (SPECT). Results 17 of 51(33.3%) patients revealed CCD phenomenon by the SPECT method. In CCD-positive group, CBF ASL of ipsilateral cerebellar were significantly increased compared with contralateral cerebellar (p < 0.0001) while no significant differences (p = 0.063, > 0.001) in the CCD-negative group. Positive correlation was detected between admission National institute of health stroke scale (NIHSS) and asymmetry index of SPECT (AI SPECT ) (r = 0.351, p = 0.011), AI ASL (r = 0.372, p = 0.007); infract volume and AI SPECT (r = 0.443, p = 0.001), AI ASL (r = 0.426, p = 0.002). Significant correlation was also found between cerebral blood flow of SPECT (CBF SPECT ) and CBF ASL , AI SPECT and AI ASL (r = 0.204, p = 0.04; r = 0.467, p = 0.001, respectively). Furthermore, the area under the receiver operating characteristic (ROC) curve value of AI ASL was 0.829. Conclusions CBF derived from ASL-MRI could be valuable for assessment of CCD in supratentorial stroke patients. Additionally, CCD was significantly associated with larger ischemic volume and higher initial NIHSS score.http://link.springer.com/article/10.1186/s12868-020-00595-zCrossed cerebellar diaschisisArterial spin-labelingSingle-photon emission CTStroke |
| spellingShingle | Juan Wang Li-Jun Pan Bin Zhou Jin-Yan Zu Yi-Xu Zhao Yang Li Wan-Qiu Zhu Lei Li Jian-Rong Xu Zeng-Ai Chen Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging BMC Neuroscience Crossed cerebellar diaschisis Arterial spin-labeling Single-photon emission CT Stroke |
| title | Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging |
| title_full | Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging |
| title_fullStr | Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging |
| title_full_unstemmed | Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging |
| title_short | Crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin-labeling MR imaging |
| title_sort | crossed cerebellar diaschisis after stroke detected noninvasively by arterial spin labeling mr imaging |
| topic | Crossed cerebellar diaschisis Arterial spin-labeling Single-photon emission CT Stroke |
| url | http://link.springer.com/article/10.1186/s12868-020-00595-z |
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