Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection
Abstract Background To date, there is a scarcity of information and literature on Macaca maura health status relative to viral diseases. The objectives of the present study were to investigate on the potential spread of enteric and non-enteric viruses shed in the environment through a wild macaque f...
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12917-022-03506-y |
| _version_ | 1811315052167299072 |
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| author | Giusy Cardeti Antonella Cersini Giuseppe Manna Paola De Santis Maria Teresa Scicluna Alessandro Albani Massimiliano Simula Stefania Sittinieri Laura De Santis Claudio De Liberato Putu Oka Ngakan Isra Wahid Monica Carosi |
| author_facet | Giusy Cardeti Antonella Cersini Giuseppe Manna Paola De Santis Maria Teresa Scicluna Alessandro Albani Massimiliano Simula Stefania Sittinieri Laura De Santis Claudio De Liberato Putu Oka Ngakan Isra Wahid Monica Carosi |
| author_sort | Giusy Cardeti |
| collection | DOAJ |
| description | Abstract Background To date, there is a scarcity of information and literature on Macaca maura health status relative to viral diseases. The objectives of the present study were to investigate on the potential spread of enteric and non-enteric viruses shed in the environment through a wild macaque feces and to understand the possible interrelation in the spread of zoonotic viruses in a poorly studied geographical area, the Sulawesi Island. This study will also contribute providing useful information on potential threats to the health of this endangered species. Methods The sampling was conducted between 2014 and 2016 in the Bantimurung Bulusaraung National Park, in the south of the Sulawesi Island and non-invasive sampling methods were used to collect fresh stools of the M. maura, one of the seven macaque species endemic to the island of Sulawesi, Indonesia. The population under study consisted in two wild, neighboring social macaque groups with partially overlapping home ranges; twenty-four samples were collected and examined using negative staining electron microscopy and a panel of PCR protocols for the detection of ten RNA and two DNA viruses. Results Viral particles resembling parvovirus (5 samples), picornavirus (13 samples) and calicivirus (13 samples) were detected by electron microscopy whereas the PCR panel was negative for the 12 viruses investigated, except for one sample positive for a mosquito flavivirus. The results did not correlate with animal sex; furthermore, because all of the animals were clinically healthy, it was not possible to correlate feces consistency with viral presence. Conclusions As information on viral infections in wild moor macaques remains limited, further studies are yet required to identify the fecal–oral and blood transmitted potentially zoonotic viruses, which may infect the moor macaque and other macaque species endemic to the South Sulawesi Island. |
| first_indexed | 2024-04-13T11:23:22Z |
| format | Article |
| id | doaj.art-9c034f93241f4d649d28383873395dd4 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-04-13T11:23:22Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-9c034f93241f4d649d28383873395dd42022-12-22T02:48:46ZengBMCBMC Veterinary Research1746-61482022-11-0118111110.1186/s12917-022-03506-yDetection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infectionGiusy Cardeti0Antonella Cersini1Giuseppe Manna2Paola De Santis3Maria Teresa Scicluna4Alessandro Albani5Massimiliano Simula6Stefania Sittinieri7Laura De Santis8Claudio De Liberato9Putu Oka Ngakan10Isra Wahid11Monica Carosi12Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Department of Sciences, Roma Tre UniversityIstituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Istituto Zooprofilattico Sperimentale del Lazio e della Toscana “M. Aleandri”Faculty of Forestry, Hasanuddin UniversityFaculty of Medicine, Hasanuddin UniversityDepartment of Sciences, Roma Tre UniversityAbstract Background To date, there is a scarcity of information and literature on Macaca maura health status relative to viral diseases. The objectives of the present study were to investigate on the potential spread of enteric and non-enteric viruses shed in the environment through a wild macaque feces and to understand the possible interrelation in the spread of zoonotic viruses in a poorly studied geographical area, the Sulawesi Island. This study will also contribute providing useful information on potential threats to the health of this endangered species. Methods The sampling was conducted between 2014 and 2016 in the Bantimurung Bulusaraung National Park, in the south of the Sulawesi Island and non-invasive sampling methods were used to collect fresh stools of the M. maura, one of the seven macaque species endemic to the island of Sulawesi, Indonesia. The population under study consisted in two wild, neighboring social macaque groups with partially overlapping home ranges; twenty-four samples were collected and examined using negative staining electron microscopy and a panel of PCR protocols for the detection of ten RNA and two DNA viruses. Results Viral particles resembling parvovirus (5 samples), picornavirus (13 samples) and calicivirus (13 samples) were detected by electron microscopy whereas the PCR panel was negative for the 12 viruses investigated, except for one sample positive for a mosquito flavivirus. The results did not correlate with animal sex; furthermore, because all of the animals were clinically healthy, it was not possible to correlate feces consistency with viral presence. Conclusions As information on viral infections in wild moor macaques remains limited, further studies are yet required to identify the fecal–oral and blood transmitted potentially zoonotic viruses, which may infect the moor macaque and other macaque species endemic to the South Sulawesi Island.https://doi.org/10.1186/s12917-022-03506-yWildlifeSulawesiNon-human primatesMacaca mauraEnteric virusTransmissible |
| spellingShingle | Giusy Cardeti Antonella Cersini Giuseppe Manna Paola De Santis Maria Teresa Scicluna Alessandro Albani Massimiliano Simula Stefania Sittinieri Laura De Santis Claudio De Liberato Putu Oka Ngakan Isra Wahid Monica Carosi Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection BMC Veterinary Research Wildlife Sulawesi Non-human primates Macaca maura Enteric virus Transmissible |
| title | Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection |
| title_full | Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection |
| title_fullStr | Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection |
| title_full_unstemmed | Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection |
| title_short | Detection of viruses from feces of wild endangered Macaca maura: a potential threat to moor macaque survival and for zoonotic infection |
| title_sort | detection of viruses from feces of wild endangered macaca maura a potential threat to moor macaque survival and for zoonotic infection |
| topic | Wildlife Sulawesi Non-human primates Macaca maura Enteric virus Transmissible |
| url | https://doi.org/10.1186/s12917-022-03506-y |
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