BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review.
BACKGROUND: Thyroid cancer incidence rates have been increasing worldwide but the reason behind this is unclear. Both the increasing use of diagnostic technologies allowing the detection of thyroid cancer and a true increase in thyroid cancer incidence have been proposed. This review assesses the ro...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3261873?pdf=render |
| _version_ | 1817995951928770560 |
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| author | Emily Peterson Prithwish De Robert Nuttall |
| author_facet | Emily Peterson Prithwish De Robert Nuttall |
| author_sort | Emily Peterson |
| collection | DOAJ |
| description | BACKGROUND: Thyroid cancer incidence rates have been increasing worldwide but the reason behind this is unclear. Both the increasing use of diagnostic technologies allowing the detection of thyroid cancer and a true increase in thyroid cancer incidence have been proposed. This review assesses the role of body mass index (BMI), diet, and reproductive factors on the thyroid cancer trend. METHODS: Epidemiologic studies of the selected risk factors up to June 2010 were reviewed and critically assessed. RESULTS: Among the thirty-seven studies reviewed and despite variation in the risk estimates, most papers supported a small but positive association for BMI (risk estimate range: 1.1-2.3 in males and 1.0-7.4 in females.). Among specific dietary components, there was no consistent association of thyroid cancer risk with iodine intake through fortification (risk estimate range: 0.49-1.6) or fish consumption (risk estimate range 0.6-2.2), nor with diets high in cruciferous vegetables (risk estimate range 0.6-1.9). A small number of studies showed a consistent protective effect of diets high in non-cruciferous vegetable (risk estimate range: 0.71-0.92). Among reproductive factors (pregnancy, parity, number of live births, use of prescription hormones, menstrual cycle regularity, and menopausal status), none were consistently associated with higher thyroid cancer risk. CONCLUSIONS: BMI had the strongest link to thyroid cancer risk among those examined. Detailed examinations of population-level risk factors can help identify and support prevention efforts to reduce the burden of thyroid cancer. |
| first_indexed | 2024-04-14T02:14:38Z |
| format | Article |
| id | doaj.art-9c06e3a9e0ea476caafc3467b584bf37 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-14T02:14:38Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-9c06e3a9e0ea476caafc3467b584bf372022-12-22T02:18:16ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0171e2917710.1371/journal.pone.0029177BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review.Emily PetersonPrithwish DeRobert NuttallBACKGROUND: Thyroid cancer incidence rates have been increasing worldwide but the reason behind this is unclear. Both the increasing use of diagnostic technologies allowing the detection of thyroid cancer and a true increase in thyroid cancer incidence have been proposed. This review assesses the role of body mass index (BMI), diet, and reproductive factors on the thyroid cancer trend. METHODS: Epidemiologic studies of the selected risk factors up to June 2010 were reviewed and critically assessed. RESULTS: Among the thirty-seven studies reviewed and despite variation in the risk estimates, most papers supported a small but positive association for BMI (risk estimate range: 1.1-2.3 in males and 1.0-7.4 in females.). Among specific dietary components, there was no consistent association of thyroid cancer risk with iodine intake through fortification (risk estimate range: 0.49-1.6) or fish consumption (risk estimate range 0.6-2.2), nor with diets high in cruciferous vegetables (risk estimate range 0.6-1.9). A small number of studies showed a consistent protective effect of diets high in non-cruciferous vegetable (risk estimate range: 0.71-0.92). Among reproductive factors (pregnancy, parity, number of live births, use of prescription hormones, menstrual cycle regularity, and menopausal status), none were consistently associated with higher thyroid cancer risk. CONCLUSIONS: BMI had the strongest link to thyroid cancer risk among those examined. Detailed examinations of population-level risk factors can help identify and support prevention efforts to reduce the burden of thyroid cancer.http://europepmc.org/articles/PMC3261873?pdf=render |
| spellingShingle | Emily Peterson Prithwish De Robert Nuttall BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review. PLoS ONE |
| title | BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review. |
| title_full | BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review. |
| title_fullStr | BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review. |
| title_full_unstemmed | BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review. |
| title_short | BMI, diet and female reproductive factors as risks for thyroid cancer: a systematic review. |
| title_sort | bmi diet and female reproductive factors as risks for thyroid cancer a systematic review |
| url | http://europepmc.org/articles/PMC3261873?pdf=render |
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