Code Blue: Life-threatening Methemoglobinemia

Most cases of acquired methemoglobinemia result from exposure to certain drugs or toxins. One of the more common and well-described causes in the literature is exposure to topical benzocaine during medical procedures. We present a case series of acute acquired methemoglobinemia from a food source th...

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Main Authors: José D. Ponce Ríos, Rothsovann Yong, Paul Calner
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2019-05-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/7xb835kj
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author José D. Ponce Ríos
Rothsovann Yong
Paul Calner
author_facet José D. Ponce Ríos
Rothsovann Yong
Paul Calner
author_sort José D. Ponce Ríos
collection DOAJ
description Most cases of acquired methemoglobinemia result from exposure to certain drugs or toxins. One of the more common and well-described causes in the literature is exposure to topical benzocaine during medical procedures. We present a case series of acute acquired methemoglobinemia from a food source that has not been previously described in the literature: a dessert. Three patients, ages 5, 33, and 86 years, were brought to our emergency department by ambulance after becoming extremely ill from ingesting a dessert containing nitre powder at a family gathering. They all presented with hypotension, cyanosis, and hypoxia that was not responsive to oxygen administration. The adult patients had major improvement of symptoms after a single dose of methylene blue. In contrast, the 5-year-old child who had the worst symptoms minimally improved with administration of two doses of methylene blue requiring intensive care admission and transfer to a tertiary care center.
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spelling doaj.art-9c074eb048d54b2eb2d0b0b12eb9e5282022-12-22T01:57:04ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2019-05-013210.5811/cpcem.2019.3.41794cpcem-03-95Code Blue: Life-threatening MethemoglobinemiaJosé D. Ponce Ríos0Rothsovann Yong1Paul Calner2Lowell General Hospital, Department of Pediatric Emergency Medicine, Lowell, MassachusettsLowell General Hospital, Department of Emergency Medicine, Lowell, MassachusettsLowell General Hospital, Department of Emergency Medicine, Lowell, MassachusettsMost cases of acquired methemoglobinemia result from exposure to certain drugs or toxins. One of the more common and well-described causes in the literature is exposure to topical benzocaine during medical procedures. We present a case series of acute acquired methemoglobinemia from a food source that has not been previously described in the literature: a dessert. Three patients, ages 5, 33, and 86 years, were brought to our emergency department by ambulance after becoming extremely ill from ingesting a dessert containing nitre powder at a family gathering. They all presented with hypotension, cyanosis, and hypoxia that was not responsive to oxygen administration. The adult patients had major improvement of symptoms after a single dose of methylene blue. In contrast, the 5-year-old child who had the worst symptoms minimally improved with administration of two doses of methylene blue requiring intensive care admission and transfer to a tertiary care center.https://escholarship.org/uc/item/7xb835kj
spellingShingle José D. Ponce Ríos
Rothsovann Yong
Paul Calner
Code Blue: Life-threatening Methemoglobinemia
Clinical Practice and Cases in Emergency Medicine
title Code Blue: Life-threatening Methemoglobinemia
title_full Code Blue: Life-threatening Methemoglobinemia
title_fullStr Code Blue: Life-threatening Methemoglobinemia
title_full_unstemmed Code Blue: Life-threatening Methemoglobinemia
title_short Code Blue: Life-threatening Methemoglobinemia
title_sort code blue life threatening methemoglobinemia
url https://escholarship.org/uc/item/7xb835kj
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AT rothsovannyong codebluelifethreateningmethemoglobinemia
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