Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample

Introduction: Paralytic ileus is a common clinical condition leading to significant morbidity and mortality. Most studies to date have focused on postoperative ileus, a common but not exclusive cause of the condition. There are limited epidemiological data regarding the incidence and impact of paral...

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Main Authors: Shantanu Solanki, Raja Chandra Chakinala, Khwaja Fahad Haq, Jagmeet Singh, Muhammad Ali Khan, Dhanshree Solanki, Manasee J Vyas, Asim Kichloo, Uvesh Mansuri, Harshil Shah, Achint Patel, Khwaja Saad Haq, Umair Iqbal, Christopher Nabors, Hafiz Muzaffar Akbar Khan, Wilbert S Aronow
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/2050312120962636
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author Shantanu Solanki
Raja Chandra Chakinala
Khwaja Fahad Haq
Jagmeet Singh
Muhammad Ali Khan
Dhanshree Solanki
Manasee J Vyas
Asim Kichloo
Uvesh Mansuri
Harshil Shah
Achint Patel
Khwaja Saad Haq
Umair Iqbal
Christopher Nabors
Hafiz Muzaffar Akbar Khan
Wilbert S Aronow
author_facet Shantanu Solanki
Raja Chandra Chakinala
Khwaja Fahad Haq
Jagmeet Singh
Muhammad Ali Khan
Dhanshree Solanki
Manasee J Vyas
Asim Kichloo
Uvesh Mansuri
Harshil Shah
Achint Patel
Khwaja Saad Haq
Umair Iqbal
Christopher Nabors
Hafiz Muzaffar Akbar Khan
Wilbert S Aronow
author_sort Shantanu Solanki
collection DOAJ
description Introduction: Paralytic ileus is a common clinical condition leading to significant morbidity and mortality. Most studies to date have focused on postoperative ileus, a common but not exclusive cause of the condition. There are limited epidemiological data regarding the incidence and impact of paralytic ileus and its relationship to other clinical conditions. In this cross-sectional study, we analyzed national inpatient hospitalization trends, demographic variation, cost of care, length of stay, and mortality for paralytic ileus hospitalizations as a whole. Methods: The National Inpatient Sample database was used to identify all hospitalizations with the diagnosis of paralytic ileus (International Classification of Diseases, 9th Revision code 560.1) as primary or secondary diagnosis during the period from 2001 to 2011. Statistical analysis was performed using Cochran–Armitage trend test, Wilcoxon rank sum test, and Poisson regression. Results: In 2001, there were 362,561 hospitalizations with the diagnosis of paralytic ileus as compared to 470,110 in 2011 (p < 0.0001). The age group 65–79 years was most commonly affected by paralytic ileus throughout the study period. In-hospital all-cause mortality decreased from 6.03% in 2001 to 5.10% in 2011 (p < 0.0001). However, the average cost of care per hospitalization increased from US$19,739 in 2001 to US$26,198 in 2011 (adjusted for inflation, p < 0.0001). Conclusion: There was a significant rise in the number of hospitalizations of paralytic ileus with increased cost of care and reduced all-cause mortality.
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spelling doaj.art-9c08ad871c02454d84bbae6feff5386f2022-12-22T02:44:01ZengSAGE PublishingSAGE Open Medicine2050-31212020-10-01810.1177/2050312120962636Paralytic ileus in the United States: A cross-sectional study from the national inpatient sampleShantanu Solanki0Raja Chandra Chakinala1Khwaja Fahad Haq2Jagmeet Singh3Muhammad Ali Khan4Dhanshree Solanki5Manasee J Vyas6Asim Kichloo7Uvesh Mansuri8Harshil Shah9Achint Patel10Khwaja Saad Haq11Umair Iqbal12Christopher Nabors13Hafiz Muzaffar Akbar Khan14Wilbert S Aronow15Department of Medicine, Geisinger Commonwealth School of Medicine, Scranton, PA, USAGuthrie Robert Packer Hospital, Sayre, PA, USADivision of Gastroenterology, Henry Ford Hospital, Detroit, MI, USADepartment of Medicine, Geisinger Commonwealth School of Medicine, Scranton, PA, USADivision of Gastroenterology, The University of Tennessee Health Science Center, Memphis, TN, USARutgers University, Piscataway, NJ, USAMahatma Gandhi Mission Institute of Health Sciences, Navi Mumbai, IndiaDepartment of Medicine, Central Michigan University, Saginaw, MI, USADepartment of Medicine, MedStar Health, Baltimore, MD, USAIndependent Researcher, Sayre, PA, USAIndependent Researcher, Sayre, PA, USADepartment of Medicine, Kingsbrook Jewish Medical Center, Brooklyn, NY, USADepartment of Medicine, Geisinger Health, Danville, PA, USADepartment of Medicine, Westchester Medical Center, Valhalla, NY, USADivision of Gastroenterology, Guthrie Robert Packer Hospital, Sayre, PA, USADivision of Cardiology, Westchester Medical Center, Valhalla, NY, USAIntroduction: Paralytic ileus is a common clinical condition leading to significant morbidity and mortality. Most studies to date have focused on postoperative ileus, a common but not exclusive cause of the condition. There are limited epidemiological data regarding the incidence and impact of paralytic ileus and its relationship to other clinical conditions. In this cross-sectional study, we analyzed national inpatient hospitalization trends, demographic variation, cost of care, length of stay, and mortality for paralytic ileus hospitalizations as a whole. Methods: The National Inpatient Sample database was used to identify all hospitalizations with the diagnosis of paralytic ileus (International Classification of Diseases, 9th Revision code 560.1) as primary or secondary diagnosis during the period from 2001 to 2011. Statistical analysis was performed using Cochran–Armitage trend test, Wilcoxon rank sum test, and Poisson regression. Results: In 2001, there were 362,561 hospitalizations with the diagnosis of paralytic ileus as compared to 470,110 in 2011 (p < 0.0001). The age group 65–79 years was most commonly affected by paralytic ileus throughout the study period. In-hospital all-cause mortality decreased from 6.03% in 2001 to 5.10% in 2011 (p < 0.0001). However, the average cost of care per hospitalization increased from US$19,739 in 2001 to US$26,198 in 2011 (adjusted for inflation, p < 0.0001). Conclusion: There was a significant rise in the number of hospitalizations of paralytic ileus with increased cost of care and reduced all-cause mortality.https://doi.org/10.1177/2050312120962636
spellingShingle Shantanu Solanki
Raja Chandra Chakinala
Khwaja Fahad Haq
Jagmeet Singh
Muhammad Ali Khan
Dhanshree Solanki
Manasee J Vyas
Asim Kichloo
Uvesh Mansuri
Harshil Shah
Achint Patel
Khwaja Saad Haq
Umair Iqbal
Christopher Nabors
Hafiz Muzaffar Akbar Khan
Wilbert S Aronow
Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample
SAGE Open Medicine
title Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample
title_full Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample
title_fullStr Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample
title_full_unstemmed Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample
title_short Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample
title_sort paralytic ileus in the united states a cross sectional study from the national inpatient sample
url https://doi.org/10.1177/2050312120962636
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