Treatment and Prevention of Recurrent <em>Clostridium difficile</em> Infection with Functionalized Bovine Antibody-Enriched Whey in a Hamster Primary Infection Model

Treatment and Prevention of Recurrent <em>Clostridium difficile</em> Infection with Functionalized Bovine Antibody-Enriched Whey in a Hamster Primary Infection Model

Toxin-induced <i>Clostridium difficile</i> infection (CDI) is a major disease characterized by severe diarrhea and high morbidity rates. The aim with this study was to develop an alternative drug for the treatment of CDI. Cows were repeatedly immunized to establish specific immunoglobuli...

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Bibliographic Details
Main Authors: Hans-Jürgen Heidebrecht, William J Weiss, Mark Pulse, Anton Lange, Karina Gisch, Heike Kliem, Sacha Mann, Michael W. Pfaffl, Ulrich Kulozik, Christoph von Eichel-Streiber
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Toxins
Subjects:
<i>Clostridium difficile</i> infection
sIgA
bovine milk
prevention of recurrence
hamster model of CDI
Online Access:https://www.mdpi.com/2072-6651/11/2/98

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