Association between Acid-Base Balance and Asphyxia in Newborn Infants

We performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical...

Full description

Bibliographic Details
Main Authors: Sari Leyli Harahap, Chairul Adillah Harahap, Sri Sulastri, Chairul Yoel, Noersida Raid
Format: Article
Language:English
Published: Indonesian Pediatric Society Publishing House 2018-11-01
Series:Paediatrica Indonesiana
Subjects:
Online Access:https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2015
_version_ 1828315624591327232
author Sari Leyli Harahap
Chairul Adillah Harahap
Sri Sulastri
Chairul Yoel
Noersida Raid
author_facet Sari Leyli Harahap
Chairul Adillah Harahap
Sri Sulastri
Chairul Yoel
Noersida Raid
author_sort Sari Leyli Harahap
collection DOAJ
description We performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical artery. Based on 1st and 5th minutes Apgar scores, 40 (88.9%) and 21 babies (46.7%}, respectively, had asphyxia. Relation to acid-base balance was determined with the sensitivity of the 5th minute Apgar score in predicting acidotic states. It was found that Apgar score had sensitivity of 57.7% and specificity of 68.4% in predicting the acidotic states. Apgar score of > 7 was unable to. exclude the possible acidosis in 45% of cases (negative predictive value 54.1%). Gestational age had no influence on Apgar Scores. Apgar score was more sensitive to eliminate suspected acidosis in term neonates than in preterms. We recommend to perform umbilical arterial blood gas analysis to determine acidotic state in high risk newborn infants.
first_indexed 2024-04-13T17:02:27Z
format Article
id doaj.art-9c0eedd721084ff48100109a2b4999bb
institution Directory Open Access Journal
issn 0030-9311
2338-476X
language English
last_indexed 2024-04-13T17:02:27Z
publishDate 2018-11-01
publisher Indonesian Pediatric Society Publishing House
record_format Article
series Paediatrica Indonesiana
spelling doaj.art-9c0eedd721084ff48100109a2b4999bb2022-12-22T02:38:35ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2018-11-01341-2384310.14238/pi34.1-2.1994.38-432015Association between Acid-Base Balance and Asphyxia in Newborn InfantsSari Leyli Harahap0Chairul Adillah Harahap1Sri Sulastri2Chairul Yoel3Noersida Raid4Department of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North SumateraDepartment of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North SumateraDepartment of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North SumateraDepartment of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North SumateraDepartment of Child Health, Universitas Sumatera Utara Medical School/Dr. Pirngadi General Hospital, Medan, North SumateraWe performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical artery. Based on 1st and 5th minutes Apgar scores, 40 (88.9%) and 21 babies (46.7%}, respectively, had asphyxia. Relation to acid-base balance was determined with the sensitivity of the 5th minute Apgar score in predicting acidotic states. It was found that Apgar score had sensitivity of 57.7% and specificity of 68.4% in predicting the acidotic states. Apgar score of > 7 was unable to. exclude the possible acidosis in 45% of cases (negative predictive value 54.1%). Gestational age had no influence on Apgar Scores. Apgar score was more sensitive to eliminate suspected acidosis in term neonates than in preterms. We recommend to perform umbilical arterial blood gas analysis to determine acidotic state in high risk newborn infants.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2015acid-base balance; asphysia; newborn infants; apgar score
spellingShingle Sari Leyli Harahap
Chairul Adillah Harahap
Sri Sulastri
Chairul Yoel
Noersida Raid
Association between Acid-Base Balance and Asphyxia in Newborn Infants
Paediatrica Indonesiana
acid-base balance; asphysia; newborn infants; apgar score
title Association between Acid-Base Balance and Asphyxia in Newborn Infants
title_full Association between Acid-Base Balance and Asphyxia in Newborn Infants
title_fullStr Association between Acid-Base Balance and Asphyxia in Newborn Infants
title_full_unstemmed Association between Acid-Base Balance and Asphyxia in Newborn Infants
title_short Association between Acid-Base Balance and Asphyxia in Newborn Infants
title_sort association between acid base balance and asphyxia in newborn infants
topic acid-base balance; asphysia; newborn infants; apgar score
url https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2015
work_keys_str_mv AT sarileyliharahap associationbetweenacidbasebalanceandasphyxiainnewborninfants
AT chairuladillahharahap associationbetweenacidbasebalanceandasphyxiainnewborninfants
AT srisulastri associationbetweenacidbasebalanceandasphyxiainnewborninfants
AT chairulyoel associationbetweenacidbasebalanceandasphyxiainnewborninfants
AT noersidaraid associationbetweenacidbasebalanceandasphyxiainnewborninfants