Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months
Purpose: To report a case with unusual initial manifestation of uveal melanoma in a 46-year-old adult. Observations: A 46-year-old man demonstrated a mid-peripheral temporal partially hyperpigmented lesion in his left eye. Initial clinical appearance as well as multimodal imaging approaches were sim...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-06-01
|
| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S245199362200264X |
| _version_ | 1818211808809320448 |
|---|---|
| author | Olga Furashova Katrin Engelmann Antonia M. Joussen Aline I. Riechardt |
| author_facet | Olga Furashova Katrin Engelmann Antonia M. Joussen Aline I. Riechardt |
| author_sort | Olga Furashova |
| collection | DOAJ |
| description | Purpose: To report a case with unusual initial manifestation of uveal melanoma in a 46-year-old adult. Observations: A 46-year-old man demonstrated a mid-peripheral temporal partially hyperpigmented lesion in his left eye. Initial clinical appearance as well as multimodal imaging approaches were similar to a chorioretinitic disease. Over the course of 9 months, a massive tumor growth and exudative retinal detachment could be observed. The diagnosis of choroidal melanoma was histopathologically confirmed after endoresection. Conclusions and importance: Classical choroidal melanoma manifest as pigmented, prominent tumors with >2 mm tumor thickness, exudative retinal detachment, and orange pigment. In our case, none of these classical clinical characteristic signs of melanoma were present at initial presentation, but the tumor underwent progressive development with significant tumor growth and exudative retinal detachment during the following 9 months. |
| first_indexed | 2024-12-12T05:38:23Z |
| format | Article |
| id | doaj.art-9c101b48c77b4abdb8695b5e1a2cea44 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-12T05:38:23Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-9c101b48c77b4abdb8695b5e1a2cea442022-12-22T00:36:01ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-06-0126101518Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 monthsOlga Furashova0Katrin Engelmann1Antonia M. Joussen2Aline I. Riechardt3Department of Ophthalmology, Klinikum Chemnitz gGmbH, Flemmingstrasse 2, 09116, Chemnitz, Germany; Corresponding author.Department of Ophthalmology, Klinikum Chemnitz gGmbH, Flemmingstrasse 2, 09116, Chemnitz, GermanyDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, GermanyDepartment of Ophthalmology, Charité - Universitätsmedizin Berlin, Berlin, GermanyPurpose: To report a case with unusual initial manifestation of uveal melanoma in a 46-year-old adult. Observations: A 46-year-old man demonstrated a mid-peripheral temporal partially hyperpigmented lesion in his left eye. Initial clinical appearance as well as multimodal imaging approaches were similar to a chorioretinitic disease. Over the course of 9 months, a massive tumor growth and exudative retinal detachment could be observed. The diagnosis of choroidal melanoma was histopathologically confirmed after endoresection. Conclusions and importance: Classical choroidal melanoma manifest as pigmented, prominent tumors with >2 mm tumor thickness, exudative retinal detachment, and orange pigment. In our case, none of these classical clinical characteristic signs of melanoma were present at initial presentation, but the tumor underwent progressive development with significant tumor growth and exudative retinal detachment during the following 9 months.http://www.sciencedirect.com/science/article/pii/S245199362200264XChoroidal melanomaUveal melanomaUnusual manifestationMasquerade syndrome |
| spellingShingle | Olga Furashova Katrin Engelmann Antonia M. Joussen Aline I. Riechardt Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months American Journal of Ophthalmology Case Reports Choroidal melanoma Uveal melanoma Unusual manifestation Masquerade syndrome |
| title | Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months |
| title_full | Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months |
| title_fullStr | Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months |
| title_full_unstemmed | Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months |
| title_short | Unusual initial manifestation of choroidal melanoma in a 46-year-old adult with rapid growth over 9 months |
| title_sort | unusual initial manifestation of choroidal melanoma in a 46 year old adult with rapid growth over 9 months |
| topic | Choroidal melanoma Uveal melanoma Unusual manifestation Masquerade syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S245199362200264X |
| work_keys_str_mv | AT olgafurashova unusualinitialmanifestationofchoroidalmelanomaina46yearoldadultwithrapidgrowthover9months AT katrinengelmann unusualinitialmanifestationofchoroidalmelanomaina46yearoldadultwithrapidgrowthover9months AT antoniamjoussen unusualinitialmanifestationofchoroidalmelanomaina46yearoldadultwithrapidgrowthover9months AT alineiriechardt unusualinitialmanifestationofchoroidalmelanomaina46yearoldadultwithrapidgrowthover9months |