Design and Optimization of In Situ Gelling Mucoadhesive Eye Drops Containing Dexamethasone

Design and Optimization of In Situ Gelling Mucoadhesive Eye Drops Containing Dexamethasone

Poor bioavailability of eye drops is a well-known issue, which can be improved by increasing the residence time on the eye surface and the penetration of the active pharmaceutical ingredient (API). This study aims to formulate in situ gelling mucoadhesive ophthalmic preparations. To increase the res...

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Bibliographic Details
Main Authors: Boglárka Szalai, Orsolya Jójárt-Laczkovich, Anita Kovács, Szilvia Berkó, György Tibor Balogh, Gábor Katona, Mária Budai-Szűcs
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Gels
Subjects:
corneal-PAMPA
cyclodextrin
factorial design
ophthalmic delivery
penetration
poloxamer 407
Online Access:https://www.mdpi.com/2310-2861/8/9/561

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