Actin filament attachments for sustained motility in vitro are maintained by filament bundling.

We reconstructed cellular motility in vitro from individual proteins to investigate how actin filaments are organized at the leading edge. Using total internal reflection fluorescence microscopy of actin filaments, we tested how profilin, Arp2/3, and capping protein (CP) function together to propel...

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Detalles Bibliográficos
Main Authors: Xiaohua Hu, Jeffrey R Kuhn
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3281059?pdf=render