Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst
Savlon (0.5% cetrimide/0.05% chlorhexidine) is used as a scolicidal during surgery of hydatid cysts. It is considered a safe and effective agent. However, there are no recommendations for the appropriate concentration or dosage of these agents. Previously reported to cause severe metabolic acidosis,...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Annals of Cardiac Anaesthesia |
| Subjects: | |
| Online Access: | http://www.annals.in/article.asp?issn=0971-9784;year=2016;volume=19;issue=3;spage=557;epage=560;aulast=Tripathy |
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| author | Swagata Tripathy Prakash Sasmal P Bhaskar Rao Tushar S Mishra Sukdev Nayak |
| author_facet | Swagata Tripathy Prakash Sasmal P Bhaskar Rao Tushar S Mishra Sukdev Nayak |
| author_sort | Swagata Tripathy |
| collection | DOAJ |
| description | Savlon (0.5% cetrimide/0.05% chlorhexidine) is used as a scolicidal during surgery of hydatid cysts. It is considered a safe and effective agent. However, there are no recommendations for the appropriate concentration or dosage of these agents. Previously reported to cause severe metabolic acidosis, its effects on the pulmonary system have not been explored. We present a case of acute lung injury and respiratory distress along with acute cardiopulmonary distress, severe metabolic acidosis, and renal failure following its use during surgical removal of pulmonary hydatid cyst. The agent may act as a chemical sclerosant causing pulmonary parenchymal damage through bronchial openings present in the pericyst. Till safe dose limits are known, use of this agent should be limited, especially in large or multiple cyst surgery. |
| first_indexed | 2024-12-10T11:25:03Z |
| format | Article |
| id | doaj.art-9c1943ccdac2492da1935400607f93d1 |
| institution | Directory Open Access Journal |
| issn | 0971-9784 |
| language | English |
| last_indexed | 2024-12-10T11:25:03Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Cardiac Anaesthesia |
| spelling | doaj.art-9c1943ccdac2492da1935400607f93d12022-12-22T01:50:47ZengWolters Kluwer Medknow PublicationsAnnals of Cardiac Anaesthesia0971-97842016-01-0119355756010.4103/0971-9784.185565Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cystSwagata TripathyPrakash SasmalP Bhaskar RaoTushar S MishraSukdev NayakSavlon (0.5% cetrimide/0.05% chlorhexidine) is used as a scolicidal during surgery of hydatid cysts. It is considered a safe and effective agent. However, there are no recommendations for the appropriate concentration or dosage of these agents. Previously reported to cause severe metabolic acidosis, its effects on the pulmonary system have not been explored. We present a case of acute lung injury and respiratory distress along with acute cardiopulmonary distress, severe metabolic acidosis, and renal failure following its use during surgical removal of pulmonary hydatid cyst. The agent may act as a chemical sclerosant causing pulmonary parenchymal damage through bronchial openings present in the pericyst. Till safe dose limits are known, use of this agent should be limited, especially in large or multiple cyst surgery.http://www.annals.in/article.asp?issn=0971-9784;year=2016;volume=19;issue=3;spage=557;epage=560;aulast=TripathyAcute lung injury; Hydatid cyst sclerosant; Metabolic acidosis; Renal failure; Savlon (0.5% cetrimide/0.05% chlorhexidine) |
| spellingShingle | Swagata Tripathy Prakash Sasmal P Bhaskar Rao Tushar S Mishra Sukdev Nayak Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst Annals of Cardiac Anaesthesia Acute lung injury; Hydatid cyst sclerosant; Metabolic acidosis; Renal failure; Savlon (0.5% cetrimide/0.05% chlorhexidine) |
| title | Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst |
| title_full | Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst |
| title_fullStr | Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst |
| title_full_unstemmed | Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst |
| title_short | Cetrimide-chlorhexidine-induced multiorgan failure in surgery of pulmonary hydatid cyst |
| title_sort | cetrimide chlorhexidine induced multiorgan failure in surgery of pulmonary hydatid cyst |
| topic | Acute lung injury; Hydatid cyst sclerosant; Metabolic acidosis; Renal failure; Savlon (0.5% cetrimide/0.05% chlorhexidine) |
| url | http://www.annals.in/article.asp?issn=0971-9784;year=2016;volume=19;issue=3;spage=557;epage=560;aulast=Tripathy |
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