Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients
Warts are benign lesions caused by infection of the keratinocytes by the human papillomavirus (HPV). There is still no consensus on the standard treatment for plantar warts, and the various treatments (both destructive and non-destructive) have variable efficacy with a long list of shortcomings, suc...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1087659/full |
| _version_ | 1797942890969694208 |
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| author | XiaoLi Chen Yan Xu Li Hu AiJun Chen |
| author_facet | XiaoLi Chen Yan Xu Li Hu AiJun Chen |
| author_sort | XiaoLi Chen |
| collection | DOAJ |
| description | Warts are benign lesions caused by infection of the keratinocytes by the human papillomavirus (HPV). There is still no consensus on the standard treatment for plantar warts, and the various treatments (both destructive and non-destructive) have variable efficacy with a long list of shortcomings, such as higher recurrence, pain, and scarring. Local hyperthermia was considered a safe, effective, and promising therapy in the treatment of plantar warts. After getting approval from the hospital’s ethics committee, the present study was designed to assess the clinical efficacy of local hyperthermia in the treatment of plantar warts. A total of 38 patients were enrolled in the study, and all patients received a standard regimen in a 5-week schedule, with local 45°C treatment for 30 mins on days 1, 2, 3, 14, 15, 22, 29, and 36. Of the 38 patients, complete resolution of the warts was observed in 13 (34.2%), 8 (21.1%) achieved partial remission, and 17 (44.7%) revealed poor response to the treatment. Patients were followed up for at least 3 months, and there was no recurrence of lesions in the 13 clinically cured patients at the last follow-up. The findings in the current study demonstrate that local hyperthermia is a safe, effective, and promising therapy for the treatment of plantar warts. |
| first_indexed | 2024-04-10T20:14:42Z |
| format | Article |
| id | doaj.art-9c1aa2ab79834e4d9f8e2f34f29055f2 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T20:14:42Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-9c1aa2ab79834e4d9f8e2f34f29055f22023-01-26T06:42:58ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-01-011010.3389/fmed.2023.10876591087659Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patientsXiaoLi ChenYan XuLi HuAiJun ChenWarts are benign lesions caused by infection of the keratinocytes by the human papillomavirus (HPV). There is still no consensus on the standard treatment for plantar warts, and the various treatments (both destructive and non-destructive) have variable efficacy with a long list of shortcomings, such as higher recurrence, pain, and scarring. Local hyperthermia was considered a safe, effective, and promising therapy in the treatment of plantar warts. After getting approval from the hospital’s ethics committee, the present study was designed to assess the clinical efficacy of local hyperthermia in the treatment of plantar warts. A total of 38 patients were enrolled in the study, and all patients received a standard regimen in a 5-week schedule, with local 45°C treatment for 30 mins on days 1, 2, 3, 14, 15, 22, 29, and 36. Of the 38 patients, complete resolution of the warts was observed in 13 (34.2%), 8 (21.1%) achieved partial remission, and 17 (44.7%) revealed poor response to the treatment. Patients were followed up for at least 3 months, and there was no recurrence of lesions in the 13 clinically cured patients at the last follow-up. The findings in the current study demonstrate that local hyperthermia is a safe, effective, and promising therapy for the treatment of plantar warts.https://www.frontiersin.org/articles/10.3389/fmed.2023.1087659/fullplantar wartsclinical observation studylocal hyperthermiawarts diseaseadverse event |
| spellingShingle | XiaoLi Chen Yan Xu Li Hu AiJun Chen Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients Frontiers in Medicine plantar warts clinical observation study local hyperthermia warts disease adverse event |
| title | Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients |
| title_full | Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients |
| title_fullStr | Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients |
| title_full_unstemmed | Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients |
| title_short | Clinical observation and study of local hyperthermia for treating plantar warts: A pilot study with 38 patients |
| title_sort | clinical observation and study of local hyperthermia for treating plantar warts a pilot study with 38 patients |
| topic | plantar warts clinical observation study local hyperthermia warts disease adverse event |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1087659/full |
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