Prevention of Noise-Induced Hearing Loss In Vivo: Continuous Application of Insulin-like Growth Factor 1 and Its Effect on Inner Ear Synapses, Auditory Function and Perilymph Proteins

Prevention of Noise-Induced Hearing Loss In Vivo: Continuous Application of Insulin-like Growth Factor 1 and Its Effect on Inner Ear Synapses, Auditory Function and Perilymph Proteins

As noise-induced hearing loss (NIHL) is a leading cause of occupational diseases, there is an urgent need for the development of preventive and therapeutic interventions. To avoid user-compliance-based problems occurring with conventional protection devices, the pharmacological prevention is current...

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Bibliographic Details
Main Authors: Kathrin Malfeld, Nina Armbrecht, Andreas Pich, Holger A. Volk, Thomas Lenarz, Verena Scheper
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
temporary threshold shift
ribbon synapse
proteomics
synaptopathy
Online Access:https://www.mdpi.com/1422-0067/24/1/291

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