Impedimetric detection of mutant p53 biomarker-driven metastatic breast cancers under hyposmotic pressure.

Impedimetric detection of mutant p53 biomarker-driven metastatic breast cancers under hyposmotic pressure.

In cancer cells, the oncogenic mutant p53 (mtp53) protein is present at high levels and gain-of-function (GOF) activities with more expression of mtp53 proteins contribute to tumor growth and metastasis. Robust analytical approaches that probe the degree of metastasis of cancer cells in connection w...

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Bibliographic Details
Main Authors: Menglu Shi, Nataly Shtraizent, Alla Polotskaia, Jill Bargonetti, Hiroshi Matsui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4060997?pdf=render

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