Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects
This prospective, double-masked, contralateral study aimed to analyze and compare daytime changes in pre-lens tear film (PLTF) stability and optical quality in symptomatic subjects wearing two contact lenses (CL). A secondary goal was to assess the performance of the PLTF by using dynamic topography...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Vision |
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| Online Access: | https://www.mdpi.com/2411-5150/8/1/11 |
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| author | Rute J. Macedo-de-Araújo Laura Rico-del-Viejo Vicente Martin-Montañez António Queirós José M. González-Méijome |
| author_facet | Rute J. Macedo-de-Araújo Laura Rico-del-Viejo Vicente Martin-Montañez António Queirós José M. González-Méijome |
| author_sort | Rute J. Macedo-de-Araújo |
| collection | DOAJ |
| description | This prospective, double-masked, contralateral study aimed to analyze and compare daytime changes in pre-lens tear film (PLTF) stability and optical quality in symptomatic subjects wearing two contact lenses (CL). A secondary goal was to assess the performance of the PLTF by using dynamic topography techniques and analyzing surface asymmetry and irregularity indexes (SAI and SRI, respectively). Measurements were conducted on 20 symptomatic subjects (OSDI score > 13). Participants were fitted contralaterally and randomly with spherical Delefilcon A and Stenfilcon A CLs and underwent a series of measurements over 3 consecutive days: three in the morning (after 1–2 h of CL wear) and three in the afternoon (after 7–9 h of CL wear). High- and low-contrast visual acuity (HCVA and LCVA, respectively), pre-lens NIBUT, and dynamic topography were assessed. The contralateral fit of the two lenses allowed a direct and better comparison between them since they were exposed to the same conditions during the day. Consequently, both lenses demonstrated similar performance in HCVA, LCVA, and PLTF stability, with no statistically significant differences between them, although some fluctuations were observed throughout the day. Dynamic topography proved sensitive in evaluating temporal changes in the PLTF. The SRI index showed greater sensitivity to topographic changes due to lacrimal destabilization, making it potentially valuable for evaluating dry eye patients. |
| first_indexed | 2024-04-24T17:45:17Z |
| format | Article |
| id | doaj.art-9c1c678ff2f8472c912d29eb378a0d40 |
| institution | Directory Open Access Journal |
| issn | 2411-5150 |
| language | English |
| last_indexed | 2024-04-24T17:45:17Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vision |
| spelling | doaj.art-9c1c678ff2f8472c912d29eb378a0d402024-03-27T14:08:05ZengMDPI AGVision2411-51502024-03-01811110.3390/vision8010011Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic SubjectsRute J. Macedo-de-Araújo0Laura Rico-del-Viejo1Vicente Martin-Montañez2António Queirós3José M. González-Méijome4Clinical & Experimental Optometry Research Lab (CEORLab), University of Minho, 4710-057 Braga, PortugalClinical and Experimental Eye Research Group, Faculty of Optics and Optometry, Universidad Complutense de Madrid, 28040 Madrid, SpainOptica Moncar, Lanzarote, Canarias, 35500 Arrecife, SpainClinical & Experimental Optometry Research Lab (CEORLab), University of Minho, 4710-057 Braga, PortugalClinical & Experimental Optometry Research Lab (CEORLab), University of Minho, 4710-057 Braga, PortugalThis prospective, double-masked, contralateral study aimed to analyze and compare daytime changes in pre-lens tear film (PLTF) stability and optical quality in symptomatic subjects wearing two contact lenses (CL). A secondary goal was to assess the performance of the PLTF by using dynamic topography techniques and analyzing surface asymmetry and irregularity indexes (SAI and SRI, respectively). Measurements were conducted on 20 symptomatic subjects (OSDI score > 13). Participants were fitted contralaterally and randomly with spherical Delefilcon A and Stenfilcon A CLs and underwent a series of measurements over 3 consecutive days: three in the morning (after 1–2 h of CL wear) and three in the afternoon (after 7–9 h of CL wear). High- and low-contrast visual acuity (HCVA and LCVA, respectively), pre-lens NIBUT, and dynamic topography were assessed. The contralateral fit of the two lenses allowed a direct and better comparison between them since they were exposed to the same conditions during the day. Consequently, both lenses demonstrated similar performance in HCVA, LCVA, and PLTF stability, with no statistically significant differences between them, although some fluctuations were observed throughout the day. Dynamic topography proved sensitive in evaluating temporal changes in the PLTF. The SRI index showed greater sensitivity to topographic changes due to lacrimal destabilization, making it potentially valuable for evaluating dry eye patients.https://www.mdpi.com/2411-5150/8/1/11dynamic topographydaily disposable contact lensestear film stability |
| spellingShingle | Rute J. Macedo-de-Araújo Laura Rico-del-Viejo Vicente Martin-Montañez António Queirós José M. González-Méijome Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects Vision dynamic topography daily disposable contact lenses tear film stability |
| title | Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects |
| title_full | Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects |
| title_fullStr | Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects |
| title_full_unstemmed | Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects |
| title_short | Daytime Changes in Tear Film Parameters and Visual Acuity with New-Generation Daily Disposable Silicone Hydrogel Contact Lenses—A Double-Masked Study in Symptomatic Subjects |
| title_sort | daytime changes in tear film parameters and visual acuity with new generation daily disposable silicone hydrogel contact lenses a double masked study in symptomatic subjects |
| topic | dynamic topography daily disposable contact lenses tear film stability |
| url | https://www.mdpi.com/2411-5150/8/1/11 |
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