Intelligent Optical Tweezers with deep neural network classifiers

Optical tweezers use light to trap and manipulate mesoscopic scaled particles with high precision making them a useful tool in a plethora of natural sciences, with emphasis on biological applications. In principle, the Brownian-like dynamics reflect trapped particle properties making it a robust sou...

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Bibliographic Details
Main Authors: Rocha Vicente, Oliveira João, Guerreiro A., Jorge Pedro A. S., Silva Nuno A.
Format: Article
Language:English
Published: EDP Sciences 2022-01-01
Series:EPJ Web of Conferences
Online Access:https://www.epj-conferences.org/articles/epjconf/pdf/2022/10/epjconf_eosam2022_13029.pdf
Description
Summary:Optical tweezers use light to trap and manipulate mesoscopic scaled particles with high precision making them a useful tool in a plethora of natural sciences, with emphasis on biological applications. In principle, the Brownian-like dynamics reflect trapped particle properties making it a robust source of information. In this work, we exploit this information by plotting histogram based images of 250ms of position or displacement used as input to a Convolution Neural Network. Results of 2-fold stratified cross-validation show satisfying classifications between sizes or types of particles: Polystyrene and Polymethilmethacrylate thus highlighting the potential of CNN approaches in faster and non-invasive applications in intelligent opto and microfluidic devices using optical trapping tools.
ISSN:2100-014X