Penicillin Binding Proteins and β-Lactamases of Mycobacterium tuberculosis: Reexamination of the Historical Paradigm

Penicillin Binding Proteins and β-Lactamases of Mycobacterium tuberculosis: Reexamination of the Historical Paradigm

ABSTRACT Penicillin binding proteins (PBPs) have been extensively studied due to their importance to the physiology of bacterial cell wall peptidoglycan and as targets of the most widely used class of antibiotics, the β-lactams. The existing paradigm asserts that PBPs catalyze the final step of pept...

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Bibliographic Details
Main Authors: Gaurav Kumar, Christos Galanis, Hunter R. Batchelder, Craig A. Townsend, Gyanu Lamichhane
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mSphere
Subjects:
Mycobacterium tuberculosis
penicillin binding proteins
β-lactams
β-lactamase
Online Access:https://journals.asm.org/doi/10.1128/msphere.00039-22

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