Etiologies and characteristics of children with chief complaint of short stature
PurposeShort stature is a very common reason for visits to pediatric endocrine clinics. It could be the first sign of an underlying disease. The purpose of this study is to investigate the etiologies and general characteristics of subjects who visited an outpatient clinic due to short stature.Method...
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| Format: | Article |
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Korean Society of Pediatric Endocrinology
2015-03-01
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| Series: | Annals of Pediatric Endocrinology & Metabolism |
| Subjects: | |
| Online Access: | http://e-apem.org/upload/pdf/apem-20-34.pdf |
| _version_ | 1828865107183009792 |
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| author | Kyung Chul Song Song Lee Jin Ah Reum Kwon Hyun Wook Chae Jung Min Ahn Duk Hee Kim Ho-Seong Kim |
| author_facet | Kyung Chul Song Song Lee Jin Ah Reum Kwon Hyun Wook Chae Jung Min Ahn Duk Hee Kim Ho-Seong Kim |
| author_sort | Kyung Chul Song |
| collection | DOAJ |
| description | PurposeShort stature is a very common reason for visits to pediatric endocrine clinics. It could be the first sign of an underlying disease. The purpose of this study is to investigate the etiologies and general characteristics of subjects who visited an outpatient clinic due to short stature.MethodsWe retrospectively reviewed the medical records of 3,371 patients who visited Severance Children's Hospital with the chief complaint of short stature from 2010 to 2012. Medical history, auxological data, and laboratory tests including bone age were collected and analyzed. Chromosome studies or combined pituitary function tests were performed if needed.ResultsApproximately 89.4% of the subjects with the chief complaint of short stature who visited the outpatient clinic were of normal height, and only 10.6% of subjects were identified as having short stature. Of the subject of short stature, 44.7% were classified as having normal variant short stature; that is, familial short stature (23.0%), constitutional delay in growth (17.7%), and mixed form (3.9%). Pathological short stature was found in 193 subjects (54.2%). Among pathological short stature, most common etiology was growth hormone deficiency (GHD) (38.9%).ConclusionA majority of children had a normal height. Among children with short stature, pathological short stature and normal variants occupied a similar percentage. GHD was the most common cause of pathological short stature and found in about 20% of the children with short stature. In pathological short stature, the height, height velocity, and IGF-1 level were lower than in normal variants. |
| first_indexed | 2024-12-13T04:22:14Z |
| format | Article |
| id | doaj.art-9c282025a2cd41648dc42aa6d67f176c |
| institution | Directory Open Access Journal |
| issn | 2287-1012 2287-1292 |
| language | English |
| last_indexed | 2024-12-13T04:22:14Z |
| publishDate | 2015-03-01 |
| publisher | Korean Society of Pediatric Endocrinology |
| record_format | Article |
| series | Annals of Pediatric Endocrinology & Metabolism |
| spelling | doaj.art-9c282025a2cd41648dc42aa6d67f176c2022-12-21T23:59:45ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922015-03-01201343910.6065/apem.2015.20.1.34603Etiologies and characteristics of children with chief complaint of short statureKyung Chul Song0Song Lee Jin1Ah Reum Kwon2Hyun Wook Chae3Jung Min Ahn4Duk Hee Kim5Ho-Seong Kim6Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.Sowha Chidren's Hospital, Seoul, Korea.Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Korea.PurposeShort stature is a very common reason for visits to pediatric endocrine clinics. It could be the first sign of an underlying disease. The purpose of this study is to investigate the etiologies and general characteristics of subjects who visited an outpatient clinic due to short stature.MethodsWe retrospectively reviewed the medical records of 3,371 patients who visited Severance Children's Hospital with the chief complaint of short stature from 2010 to 2012. Medical history, auxological data, and laboratory tests including bone age were collected and analyzed. Chromosome studies or combined pituitary function tests were performed if needed.ResultsApproximately 89.4% of the subjects with the chief complaint of short stature who visited the outpatient clinic were of normal height, and only 10.6% of subjects were identified as having short stature. Of the subject of short stature, 44.7% were classified as having normal variant short stature; that is, familial short stature (23.0%), constitutional delay in growth (17.7%), and mixed form (3.9%). Pathological short stature was found in 193 subjects (54.2%). Among pathological short stature, most common etiology was growth hormone deficiency (GHD) (38.9%).ConclusionA majority of children had a normal height. Among children with short stature, pathological short stature and normal variants occupied a similar percentage. GHD was the most common cause of pathological short stature and found in about 20% of the children with short stature. In pathological short stature, the height, height velocity, and IGF-1 level were lower than in normal variants.http://e-apem.org/upload/pdf/apem-20-34.pdfShort statureEtiologyGrowth |
| spellingShingle | Kyung Chul Song Song Lee Jin Ah Reum Kwon Hyun Wook Chae Jung Min Ahn Duk Hee Kim Ho-Seong Kim Etiologies and characteristics of children with chief complaint of short stature Annals of Pediatric Endocrinology & Metabolism Short stature Etiology Growth |
| title | Etiologies and characteristics of children with chief complaint of short stature |
| title_full | Etiologies and characteristics of children with chief complaint of short stature |
| title_fullStr | Etiologies and characteristics of children with chief complaint of short stature |
| title_full_unstemmed | Etiologies and characteristics of children with chief complaint of short stature |
| title_short | Etiologies and characteristics of children with chief complaint of short stature |
| title_sort | etiologies and characteristics of children with chief complaint of short stature |
| topic | Short stature Etiology Growth |
| url | http://e-apem.org/upload/pdf/apem-20-34.pdf |
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